Lai Qi, Liu Yuan, Yu Xionglong, Lv Xin, Wang Qiang, Zhou Yibiao, Guo Runsheng, Zhang Bin
Department of Orthopedics, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, The First Affiliated Hospital of Nanchang University, 330006, Nangchang, Jiangxi, China.
Multidisciplinary Therapy Center of Musculoskeletal Tumor, The First Affiliated Hospital of Nanchang University, 330006, Nangchang, Jiangxi, China.
Orthopade. 2017 Jan;46(1):85-89. doi: 10.1007/s00132-016-3349-3.
Cryptococcal spine infections are rare infections that are easy to misdiagnose and difficult to cure. Therefore, we report the case of a 25-year-old man who presented with nonspecific spinal lesions at L1 and S1. The patient underwent surgical removal of the lesions, and specimens were submitted for microbial identification, which identified a cryptococcal infection that was susceptible to amphotericin B. The patient exhibited marked improvement after receiving intravenous amphotericin B and remained asymptomatic (no back pain, fever, or other symptoms) at the 3‑ and 9‑month follow-ups. Similar cases of cryptococcal spine infections are rare, and we believe that our diagnostic findings and treatment experience may help improve the management of this rare disease.
隐球菌性脊柱感染是罕见的感染性疾病，容易误诊且难以治愈。因此，我们报告一例25岁男性病例，该患者L1和S1节处1椎体出现非特异性脊柱病变。患者接受了病变切除术，并送检标本进行微生物鉴定，结果鉴定为对两性霉素B敏感的隐球菌感染。患者接受静脉注射两性霉素B后病情显著改善，在3个月和9个月的随访中均无症状（无背痛、发热或其他症状）。类似的隐球菌性脊柱感染病例很少见，我们认为我们的诊断结果和治疗经验可能有助于改善这种罕见疾病的管理。
