PhSO SCF3H：一种稳定、易于规模化的自由基二氟甲硫基化试剂。
PhSO SCF H: A Shelf-Stable, Easily Scalable Reagent for Radical Difluoromethylthiolation.
机构信息
Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032, China.
出版信息
Angew Chem Int Ed Engl. 2016 Dec 19;55(51):15807-15811. doi: 10.1002/anie.201609468. Epub 2016 Nov 17.
A new shelf-stable and easily scalable difluoromethylthiolating reagent S-(difluoromethyl) benzenesulfonothioate (PhSO SCF H) was developed. PhSO SCF H is a powerful reagent for radical difluoromethylthiolation of aryl and alkyl boronic acids, decarboxylative difluoromethylthiolation of aliphatic acids, and a phenylsulfonyl-difluoromethylthio difunctionalization of alkenes under mild reaction conditions.
开发了一种新型的稳定且易于规模化的二氟甲基硫代试剂 S-(二氟甲基)苯磺硫代酸酯（PhSO SCF H）。PhSO SCF H 是一种强大的试剂，可在温和的反应条件下实现芳基和烷基硼酸的自由基二氟甲基硫代化、脂肪族酸的脱羧二氟甲基硫代化以及烯烃的亚砜基-二氟甲基硫代二官能化。
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