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韩国普通人群中二手烟与喉病的关联。

Association between Second-Hand Smoking and Laryngopathy in the General Population of South Korea.

作者信息

Byeon Haewon, Lee Dongwoo, Cho Sunghyoun

机构信息

Department of Speech Language Pathology & Audiology, School of Public Health, Nambu University, Gwangju, Republic of Korea.

Department of Physical Therapy, School of Public Health, Honam University, Gwangju, Republic of Korea.

出版信息

PLoS One. 2016 Nov 18;11(11):e0165337. doi: 10.1371/journal.pone.0165337. eCollection 2016.

Abstract

PURPOSE

The relationship between second-hand smoking and laryngopathy has not yet been reported. Thus, this study investigates the relationship between second-hand smoking and laryngopathy and suggests basic empirical data to prevent laryngopathy.

METHODS

This study analyzed 1,905 non-smokers over the age of 19 (269 men and 1,636 women) who completed the health questionnaire, laryngeal endoscope test, and urine cotinine test in the 2008 Korea National Health and Nutrition Examination Survey (KNHANES). Second-hand smoking was defined as a urine cotinine concentration of 50ng/ml and over. Confounding factors included age, gender, education, household income, occupation, alcohol consumption, and coffee consumption. Risk ratios (RR) and 95% confidence intervals (CI) were presented for the relationship between second-hand smoking and laryngopathy by using Poisson regression analysis.

RESULTS

There was a significant relationship between second-hand smoking and laryngopathy (p<0.05). After all compounding factors were adjusted, non-smokers exposed to second-hand smoking had a 2.5 times (RR = 2.47, 95% CI: 1.19-5.08) significantly higher risk of laryngopathy than non-smokers not exposed to second-hand smoking (p<0.05).

CONCLUSION

In this epidemiological study, there was a significant relationship between second-hand smoking and laryngopathy. More effective anti-smoking policies are required to protect the health of both non-smokers and smokers.

摘要

目的

二手烟与喉病之间的关系尚未见报道。因此,本研究旨在调查二手烟与喉病之间的关系,并为预防喉病提供基础实证数据。

方法

本研究分析了2008年韩国国家健康与营养检查调查(KNHANES)中19岁以上的1905名不吸烟者(269名男性和1636名女性),他们完成了健康问卷、喉镜检查和尿可替宁检测。二手烟定义为尿可替宁浓度在50ng/ml及以上。混杂因素包括年龄、性别、教育程度、家庭收入、职业、饮酒和咖啡饮用情况。采用泊松回归分析呈现二手烟与喉病之间关系的风险比(RR)和95%置信区间(CI)。

结果

二手烟与喉病之间存在显著关系(p<0.05)。在调整所有混杂因素后,接触二手烟的不吸烟者患喉病的风险比未接触二手烟的不吸烟者高2.5倍(RR = 2.47,95% CI:1.19 - 5.08),差异有统计学意义(p<0.05)。

结论

在这项流行病学研究中,二手烟与喉病之间存在显著关系。需要更有效的禁烟政策来保护不吸烟者和吸烟者的健康。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08b7/5115661/c31af9e473fd/pone.0165337.g001.jpg

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