Maternal-Infant Care Research Centre, Mount Sinai Hospital, Toronto, ON, Canada.
UK Neonatal Collaborative, Neonatal Data Analysis Unit, Section of Neonatal Medicine, Department of Medicine, Imperial College London, London, UK.
Acta Paediatr. 2017 Mar;106(3):366-374. doi: 10.1111/apa.13672. Epub 2016 Dec 8.
The use of different definitions for bronchopulmonary dysplasia (BPD) has been an ongoing challenge. We searched papers published in English from 2010 and 2015 reporting BPD as an outcome, together with studies that compared BPD definitions between 1978 and 2015. We found that the incidence of BPD ranged from 6% to 57%, depending on the definition chosen, and that studies that investigated correlations with long-term pulmonary and/or neurosensory outcomes reported moderate-to-low predictive values regardless of the BPD criteria.
A comprehensive and evidence-based definition for BPD needs to be developed for benchmarking and prognostic use.
支气管肺发育不良(BPD)的定义一直存在争议。我们检索了 2010 年至 2015 年期间以 BPD 为结局的英文文献,并对 1978 年至 2015 年间比较 BPD 定义的研究进行了分析。结果:BPD 的发生率差异较大,为 6%至 57%,取决于选择的定义。研究显示,长期肺和/或神经发育预后与 BPD 标准相关,但预测值为中-低度。结论:BPD 定义需要综合现有证据,以用于预后判断和基准比较。