3至5岁儿童母乳中瘦素和脂联素与身体成分的关系：一项随访研究。

The relationship between breast milk leptin and adiponectin with child body composition from 3 to 5 years: a follow-up study.

作者信息

Meyer D M, Brei C, Stecher L, Much D, Brunner S, Hauner H

机构信息

From the Else Kröner-Fresenius-Center for Nutritional Medicine, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

Institute of Diabetes Research, Helmholtz Zentrum München, Forschergruppe Diabetes, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

出版信息

Pediatr Obes. 2017 Aug;12 Suppl 1:125-129. doi: 10.1111/ijpo.12192. Epub 2016 Nov 10.

DOI:10.1111/ijpo.12192

PMID:27863153

Abstract

BACKGROUND

Research indicates that breast milk contains bioactive components that influence metabolism in infancy and may play a role in the prevention of obesity in early childhood. In our initial study, 147 breastfeeding mother/child pairs were followed from birth to 2 years of age to examine the relationship between breast milk leptin and total adiponectin (collected at 6 weeks and 4 months postpartum) and infant body composition. Higher breast milk total adiponectin was related to greater fat mass and weight gain in children at 1 and 2 years of age, whereas leptin showed no association.

OBJECTIVES/METHODS: In this follow-up, we examined the relationship between both adipokines and children's body weight, body mass index percentiles, sum of four skin-folds, percentage of body fat, fat mass and lean body mass at 3, 4 and 5 years of age.

RESULTS

Breast milk adipokines were largely unrelated to child anthropometric measures.

CONCLUSION

Our results do not provide significant evidence that breast milk adipokines can predict adiposity in preschool children.

摘要

背景

研究表明，母乳含有影响婴儿期新陈代谢的生物活性成分，可能在预防幼儿肥胖方面发挥作用。在我们的初步研究中，对147对母乳喂养的母婴从出生到2岁进行跟踪，以研究母乳中瘦素和总脂联素（在产后6周和4个月采集）与婴儿身体成分之间的关系。母乳中较高的总脂联素与1岁和2岁儿童更大的脂肪量和体重增加有关，而瘦素则无关联。

目的/方法：在本次随访中，我们研究了这两种脂肪因子与3岁、4岁和5岁儿童的体重、体重指数百分位数、四处皮褶厚度之和、体脂百分比、脂肪量和去脂体重之间的关系。