Fong Zhi Ven, Fernández-Del Castillo Carlos
Department of Surgery, Massachusetts General Hospital, Harvard Medical School, 15 Parkman Street, Boston, MA 02114-3117, USA.
Department of Surgery, Massachusetts General Hospital, Harvard Medical School, 15 Parkman Street, Boston, MA 02114-3117, USA.
Surg Clin North Am. 2016 Dec;96(6):1431-1445. doi: 10.1016/j.suc.2016.07.009.
The incidence of intraductal papillary mucinous neoplasms (IPMNs) of the pancreas has been rising in the past 2 decades, driven mainly by the widespread use of cross-sectional imaging. IPMNs are intraductal mucin-producing neoplasms that involve the main pancreatic duct or its side branches and lack the ovarian stroma typically seen in mucinous cystic neoplasms. The International Association of Pancreatology released consensus guidelines in 2006 and 2012 providing clinical algorithms based on IPMN features and risk of malignancy. In this article, we review the different classifications of IPMNs, their natural history, and clinical management and address recent controversies in the literature.
在过去20年中，胰腺导管内乳头状黏液性肿瘤（IPMN）的发病率一直在上升，这主要是由于横断面成像技术的广泛应用。IPMN是一种产生导管内黏液的肿瘤，累及主胰管或其分支，且缺乏黏液性囊性肿瘤中常见的卵巢间质。国际胰腺病协会在2006年和2012年发布了共识指南，提供了基于IPMN特征和恶性风险的临床算法。在本文中，我们回顾了IPMN的不同分类、其自然病史、临床管理，并讨论了文献中最近的争议。
