Gange William S, Blackwell Robert H, Biemer John, Barkan Güliz A, Picken Maria M, Quek Marcus L
Department of Urology, Loyola University Medical Center, Maywood, Ill. USA.
Department of Pathology, Loyola University Medical Center, Maywood, Ill. USA.
Curr Urol. 2016 Oct;9(3):163-165. doi: 10.1159/000447134. Epub 2016 Sep 20.
Growing teratoma syndrome is an infrequent presentation of testicular cancer. We present a case of growing teratoma syndrome in a patient who initially presented with clinical stage I nonseminomatous testicular germ cell tumor, who subsequently developed large volume oligometastases to the retroperitoneum, thorax, and thigh. Despite two regimens of chemotherapy, his disease progressed. Complete surgical extirpation of all gross tumors confirmed mature teratoma. An aggressive surgical approach, including postchemotherapy resection of all known metastatic sites, can provide long-term disease-free survival.
生长性畸胎瘤综合征是睾丸癌的一种罕见表现。我们报告一例生长性畸胎瘤综合征患者,该患者最初表现为临床I期非精原性睾丸生殖细胞肿瘤,随后出现大量寡转移至腹膜后、胸部和大腿。尽管接受了两种化疗方案,其疾病仍进展。所有肉眼可见肿瘤的完整手术切除证实为成熟畸胎瘤。积极的手术方法,包括化疗后切除所有已知转移部位,可提供长期无病生存。