Polańska Kinga, Hanke Wojciech, Król Anna, Potocka Adrianna, Waszkowska Małgorzata, Jacukowicz Aleksandra, Gromadzińska Jolanta, Wąsowicz Wojciech, Jerzyńska Joanna, Stelmach Włodzimierz, Stelmach Iwona
Nofer Institute of Occupational Medicine, Łódź, Poland (Department of Environmental Epidemiology).
Nofer Institute of Occupational Medicine, Łódź, Poland (Department of Health and Work Psychology).
Int J Occup Med Environ Health. 2016 Nov 18;29(6):883-893. doi: 10.13075/ijomeh.1896.00811. Epub 2016 Oct 21.
Effects of environmental exposures in utero and in the first years of life on early life health and development is a growing research area with major public health implications. The main aim of this work has been to provide an overview of the next step of the Polish Mother and Child Cohort Study (REPRO_PL) covering exposure, health and neurodevelopment assessments of children at 7 years of age. Details regarding methodology of the follow-up of the children are crucial for cross-cohort collaboration and a full understanding of the future research questions. Phase III of the REPRO_PL cohort covers a follow-up of 900 children at the age of 7 years old. The questionnaire filled in by the mothers is composed of: socio-demographic, child exposure and home environment information, nutritional status and health data. In the case of 400 children, environmental (including collection of urine, saliva and buccal cells), health status and psychomotor assessments are performed. Health and development check consists of physical measurements, child health status assessment (including lung function tests, skin prick testing, an interview/examination by an allergist) and psychomotor development tests (the Strength and Difficulties Questionnaire and the Intelligence and Development Scales). The results of the study will become available within the next few years. Extension of the REPRO_PL cohort with examinations of children at the age of 7 years old may provide a better understanding of the relationship between environmental and lifestyle-related factors and children's health and neurodevelopment; and may further strengthen scientific base for policies and interventions promoting healthy lifestyle. Int J Occup Med Environ Health 2016;29(6):883-893.
子宫内及生命最初几年的环境暴露对早期生命健康和发育的影响是一个不断发展的研究领域，具有重大的公共卫生意义。这项工作的主要目的是概述波兰母婴队列研究（REPRO_PL）的下一步计划，该计划涵盖对7岁儿童的暴露、健康和神经发育评估。有关儿童随访方法的详细信息对于跨队列合作以及全面理解未来研究问题至关重要。REPRO_PL队列的第三阶段包括对900名7岁儿童的随访。母亲填写的问卷包括：社会人口统计学、儿童暴露和家庭环境信息、营养状况和健康数据。对400名儿童进行环境（包括尿液、唾液和颊细胞采集）、健康状况和心理运动评估。健康与发育检查包括身体测量、儿童健康状况评估（包括肺功能测试、皮肤点刺试验、过敏专科医生的访谈/检查）和心理运动发育测试（长处与困难问卷和智力与发育量表）。研究结果将在未来几年内得出。对REPRO_PL队列进行扩展，纳入对7岁儿童的检查，可能有助于更好地理解环境和生活方式相关因素与儿童健康和神经发育之间的关系；并可能进一步加强促进健康生活方式的政策和干预措施的科学依据。《国际职业医学与环境卫生杂志》2016年；29(6):883 - 893。
