Ziv Etay, Durack Jeremy C, Solomon Stephen B
From the Interventional Radiology Service, Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY.
Cancer J. 2016 Nov/Dec;22(6):418-422. doi: 10.1097/PPO.0000000000000228.
Recent advances in the molecular characterization of cancers have triggered interest in developing a new taxonomy of disease in oncology with the goal of using the molecular profile of a patient's tumor to predict response to treatment. Image-guided needle biopsy is central to this "precision medicine" effort. In this review, we first discuss the current role of biopsy in relation to clinical examples of molecular medicine. We then outline important bottlenecks to the advancement of precision medicine and highlight the potential role of image-guided biopsy to address these challenges.
癌症分子特征方面的最新进展引发了人们对开发肿瘤学新疾病分类法的兴趣，其目标是利用患者肿瘤的分子特征来预测治疗反应。图像引导下的针吸活检是这项“精准医学”努力的核心。在本综述中，我们首先讨论活检在分子医学临床实例方面的当前作用。然后，我们概述精准医学发展的重要瓶颈，并强调图像引导活检在应对这些挑战方面的潜在作用。
