活检在分子医学时代的重要性。
The Importance of Biopsy in the Era of Molecular Medicine.
作者信息
Ziv Etay, Durack Jeremy C, Solomon Stephen B
机构信息
From the Interventional Radiology Service, Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY.
出版信息
Cancer J. 2016 Nov/Dec;22(6):418-422. doi: 10.1097/PPO.0000000000000228.
Abstract
Recent advances in the molecular characterization of cancers have triggered interest in developing a new taxonomy of disease in oncology with the goal of using the molecular profile of a patient's tumor to predict response to treatment. Image-guided needle biopsy is central to this "precision medicine" effort. In this review, we first discuss the current role of biopsy in relation to clinical examples of molecular medicine. We then outline important bottlenecks to the advancement of precision medicine and highlight the potential role of image-guided biopsy to address these challenges.
摘要
癌症分子特征方面的最新进展引发了人们对开发肿瘤学新疾病分类法的兴趣，其目标是利用患者肿瘤的分子特征来预测治疗反应。图像引导下的针吸活检是这项“精准医学”努力的核心。在本综述中，我们首先讨论活检在分子医学临床实例方面的当前作用。然后，我们概述精准医学发展的重要瓶颈，并强调图像引导活检在应对这些挑战方面的潜在作用。
相似文献
1
The Importance of Biopsy in the Era of Molecular Medicine.活检在分子医学时代的重要性。
Cancer J. 2016 Nov/Dec;22(6):418-422. doi: 10.1097/PPO.0000000000000228.
2
Role of Image-Guided Percutaneous Needle Biopsy in the Age of Precision Medicine.影像引导经皮穿刺活检在精准医学时代的作用。
Curr Oncol Rep. 2022 Aug;24(8):1035-1044. doi: 10.1007/s11912-022-01271-7. Epub 2022 Apr 1.
3
Image-guided biopsy in the age of personalised medicine: strategies for success and safety.个体化医学时代的影像引导活检：成功和安全策略。
Clin Radiol. 2021 Feb;76(2):154.e1-154.e9. doi: 10.1016/j.crad.2020.08.010. Epub 2020 Sep 28.
4
Role of image-guided biopsy and radiomics in the age of precision medicine.图像引导活检和影像组学在精准医学时代的作用。
Chin Clin Oncol. 2019 Dec;8(6):57. doi: 10.21037/cco.2019.12.02.
5
The evolving role of image-guided biopsy and specimen fixation-update from an oncology setting.图像引导活检和标本固定在肿瘤学领域不断演变的作用——最新进展
Br J Radiol. 2019 Jun;92(1098):20180971. doi: 10.1259/bjr.20180971. Epub 2019 Apr 9.
6
[The progression of tumor liquid biopsy and its applications in precision medicine].[肿瘤液体活检的进展及其在精准医学中的应用]
Zhonghua Wai Ke Za Zhi. 2017 Jun 1;55(6):401-405. doi: 10.3760/cma.j.issn.0529-5815.2017.06.001.
7
Liquid biopsy, a paradigm shift in oncology: what interventional radiologists should know.液体活检：肿瘤学的范式转变：介入放射科医生应该知道什么。
Eur Radiol. 2020 Aug;30(8):4496-4503. doi: 10.1007/s00330-020-06700-4. Epub 2020 Mar 19.
8
Transthoracic computed tomography-guided lung biopsy in the new era of personalized medicine.个体化医学新时代的经胸 CT 引导下肺活检。
Future Oncol. 2019 Apr;15(10):1125-1134. doi: 10.2217/fon-2018-0527. Epub 2019 Mar 18.
9
Complexity of Delivering Precision Medicine: Opportunities and Challenges.提供精准医疗的复杂性：机遇与挑战。
Am Soc Clin Oncol Educ Book. 2018 May 23;38:998-1007. doi: 10.1200/EDBK_200279.
10
Incidence of major hemorrhage after aggressive image-guided liver mass biopsy in the era of individualized medicine.个体化医学时代下积极的影像引导肝肿块活检后的大出血发生率。
Abdom Radiol (NY). 2019 Jun;44(6):2067-2073. doi: 10.1007/s00261-018-1637-6.
引用本文的文献
1
Retinoblastoma: Aqueous humor liquid biopsy.视网膜母细胞瘤：房水液体活检
Taiwan J Ophthalmol. 2025 Mar 20;15(1):55-61. doi: 10.4103/tjo.TJO-D-24-00133. eCollection 2025 Jan-Mar.
2
Diagnostics and Therapy for Malignant Tumors.恶性肿瘤的诊断与治疗
Biomedicines. 2024 Nov 21;12(12):2659. doi: 10.3390/biomedicines12122659.
3
Obtention of viable cell suspensions from breast cancer tumor biopsies for 3D chromatin conformation and single-cell transcriptome analysis.从乳腺癌肿瘤活检样本中获取活细胞悬液用于三维染色质构象和单细胞转录组分析。
Front Mol Biosci. 2024 Aug 22;11:1420308. doi: 10.3389/fmolb.2024.1420308. eCollection 2024.
4
An augmented reality-guided biopsy system using a high-speed motion tracking and real-time registration platform.一种使用高速运动跟踪和实时配准平台的增强现实引导活检系统。
Proc SPIE Int Soc Opt Eng. 2024 Feb;12928. doi: 10.1117/12.3008573. Epub 2024 Mar 29.
5
Postmortem Minimally Invasive Autopsy in Critically Ill COVID-19 Patients at the Bedside: A Proof-of-Concept Study at the ICU.危重症 COVID-19 患者床边尸检微创尸检：重症监护病房的概念验证研究
Diagnostics (Basel). 2024 Jan 30;14(3):294. doi: 10.3390/diagnostics14030294.
6
Artificial intelligence fusion for predicting survival of rectal cancer patients using immunohistochemical expression of Ras homolog family member B in biopsy.利用活检中Ras同源家族成员B的免疫组化表达进行人工智能融合以预测直肠癌患者的生存情况。
Explor Target Antitumor Ther. 2023;4(1):1-16. doi: 10.37349/etat.2023.00119. Epub 2023 Feb 7.
7
Expression of Matrix Metalloproteinase-21 in Oral Squamous Cell Carcinoma.基质金属蛋白酶-21在口腔鳞状细胞癌中的表达
Cureus. 2023 Jan 27;15(1):e34256. doi: 10.7759/cureus.34256. eCollection 2023 Jan.
8
Employing radiography (X-rays) to localize lesions in human skeletal remains from past populations to allow accurate biopsy, using examples of cancer metastases.利用放射成像（X射线）对过去人群的人类骨骼遗骸中的病变进行定位，以便进行准确的活检，并以癌症转移为例。
Int J Osteoarchaeol. 2022 Jul-Aug;32(4):916-922. doi: 10.1002/oa.3087. Epub 2022 Jan 11.
9
Evaluation of an Integrated Spectroscopy and Classification Platform for Point-of-Care Core Needle Biopsy Assessment: Performance Characteristics from Ex Vivo Renal Mass Biopsies.即时护理核心针活检评估的集成光谱和分类平台的评估：来自体外肾肿块活检的性能特征。
J Vasc Interv Radiol. 2022 Nov;33(11):1408-1415.e3. doi: 10.1016/j.jvir.2022.07.027. Epub 2022 Aug 5.
10
Integrated Workflow for the Label-Free Isolation and Genomic Analysis of Single Circulating Tumor Cells in Pancreatic Cancer.用于胰腺癌中无标记循环肿瘤细胞的分离和基因组分析的集成工作流程。
Int J Mol Sci. 2022 Jul 16;23(14):7852. doi: 10.3390/ijms23147852.
本文引用的文献
1
What Happens When Underperforming Big Ideas in Research Become Entrenched?当研究中表现不佳的重大理念变得根深蒂固时会发生什么？
JAMA. 2016 Oct 4;316(13):1355-1356. doi: 10.1001/jama.2016.11076.
2
Lung Adenocarcinoma: Predictive Value of KRAS Mutation Status in Assessing Local Recurrence in Patients Undergoing Image-guided Ablation.肺腺癌：KRAS 突变状态在评估接受图像引导消融治疗患者局部复发中的预测价值
Radiology. 2017 Jan;282(1):251-258. doi: 10.1148/radiol.2016160003. Epub 2016 Jul 19.
3
Urachal Carcinoma Shares Genomic Alterations with Colorectal Carcinoma and May Respond to Epidermal Growth Factor Inhibition.脐尿管癌与结直肠癌存在共同的基因组改变，且可能对表皮生长因子抑制有反应。
Eur Urol. 2016 Nov;70(5):771-775. doi: 10.1016/j.eururo.2016.04.037. Epub 2016 May 10.
4
Biomarker-Guided Adaptive Trial Designs in Phase II and Phase III: A Methodological Review.二、三期生物标志物引导的适应性试验设计：方法学综述
PLoS One. 2016 Feb 24;11(2):e0149803. doi: 10.1371/journal.pone.0149803. eCollection 2016.
5
Image-Guided Biopsy in the Era of Personalized Cancer Care: Proceedings from the Society of Interventional Radiology Research Consensus Panel.个性化癌症治疗时代的图像引导活检：介入放射学会研究共识小组会议记录
J Vasc Interv Radiol. 2016 Jan;27(1):8-19. doi: 10.1016/j.jvir.2015.10.019. Epub 2015 Nov 25.
6
BRAF Mutation in Colorectal Cancer: An Update.结直肠癌中的BRAF突变：最新进展
Biomark Cancer. 2015 Sep 6;7(Suppl 1):9-12. doi: 10.4137/BIC.S25248. eCollection 2015.
7
A 2015 update on predictive molecular pathology and its role in targeted cancer therapy: a review focussing on clinical relevance.2015年预测性分子病理学及其在靶向癌症治疗中的作用更新：聚焦临床相关性的综述
Cancer Gene Ther. 2015 Sep;22(9):417-30. doi: 10.1038/cgt.2015.39. Epub 2015 Sep 11.
8
Grade Increases in Gastroenteropancreatic Neuroendocrine Tumor Metastases Compared to the Primary Tumor.与原发性肿瘤相比，胃肠胰神经内分泌肿瘤转移灶的分级增加。
Neuroendocrinology. 2016;103(5):452-9. doi: 10.1159/000439434. Epub 2015 Aug 25.
9
Solid Predominant Histologic Subtype in Resected Stage I Lung Adenocarcinoma Is an Independent Predictor of Early, Extrathoracic, Multisite Recurrence and of Poor Postrecurrence Survival.切除的Ⅰ期肺腺癌中实性为主的组织学亚型是早期、胸外、多部位复发及复发后生存不良的独立预测因素。
J Clin Oncol. 2015 Sep 10;33(26):2877-84. doi: 10.1200/JCO.2015.60.9818. Epub 2015 Aug 10.
10
KRAS Status as an Independent Prognostic Factor for Survival after Yttrium-90 Radioembolization Therapy for Unresectable Colorectal Cancer Liver Metastases.KRAS状态作为不可切除的结直肠癌肝转移患者钇-90放射性栓塞治疗后生存的独立预后因素
J Vasc Interv Radiol. 2015 Aug;26(8):1102-11. doi: 10.1016/j.jvir.2015.05.032.
Zotero 插件