Department of Medicine & Surgery, Unit of Radiologic Science, University of Parma, Maggiore Hospital, Via Gramsci 14, Parma, Italy.
Medical Oncology Unit, University of Parma, Maggiore Hospital, Via Gramsci 14, Parma, Italy.
Future Oncol. 2019 Apr;15(10):1125-1134. doi: 10.2217/fon-2018-0527. Epub 2019 Mar 18.
Computed tomography-guided lung biopsy is a valid and safe procedure for characterizing pulmonary nodules. In the past years, this technique has been mainly used to confirm the malignant nature of undetermined pulmonary lesions; however, today its role has been completely renewed. With the advent of target therapy and immunotherapy, it has arisen for lung cancer, in inoperable patients, the necessity to obtain adequate bioptical material to perform a correct molecular characterization of the lesion. Moreover, the possibility of acquired drug-resistance mechanisms makes it necessary in some cases to rebiopsy these lesions over time. For these reasons, it is likely that the request of computed tomography-guided lung biopsy will increase in the future, therefore every radiologist should be confident with its most important aspects.
计算机断层扫描引导下的肺活检是一种有效的、安全的方法，可用于确定肺部结节的特征。在过去的几年中，这项技术主要用于确定性质不明的肺部病变是否为恶性；然而，如今它的作用已经完全被重新定义。随着靶向治疗和免疫疗法的出现，对于不能手术的肺癌患者，有必要获得足够的生物光学材料来对病变进行正确的分子特征分析。此外，获得耐药机制的可能性使得在某些情况下有必要随着时间的推移对这些病变进行重新活检。出于这些原因，未来对计算机断层扫描引导下肺活检的需求很可能会增加，因此每个放射科医生都应该对其最重要的方面有信心。
