Chan J K, Tsang D N, Wong D K
Institute of Pathology, Queen Elizabeth Hospital, Hong Kong.
Acta Cytol. 1989 Jul-Aug;33(4):523-6.
Penicillium marneffei is a rare human pathogen that may infect either healthy or immunocompromised hosts. In methenamine silver-stained preparations of bronchoalveolar lavage fluid from a patient with dermatomyositis on steroid treatment, round-to-oval intracellular and extracellular microorganisms were found. The finding of occasional septate and elongated forms established the microorganism as probably P marneffei, which was confirmed on culture. Distinguishing this rare fungus from Pneumocystis carinii is important because these two diseases require different forms of treatment.
马尔尼菲青霉是一种罕见的人类病原体，可感染健康或免疫功能低下的宿主。在一名接受类固醇治疗的皮肌炎患者的支气管肺泡灌洗液体银染色标本中，发现了圆形至椭圆形的细胞内和细胞外微生物。偶尔出现的有隔和细长形态的发现确定该微生物可能为马尔尼菲青霉，培养结果证实了这一点。将这种罕见真菌与卡氏肺孢子菌区分开来很重要，因为这两种疾病需要不同的治疗方式。
