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1978 - 1984年苏格兰酒精性和非酒精性肝病与酒精消费的关系。第一部分:肝病流行病学

Alcoholic and non-alcoholic liver disease in relation to alcohol consumption in Scotland, 1978-84. Part I: Epidemiology of liver diseases.

作者信息

Kreitman N, Duffy J

出版信息

Br J Addict. 1989 Jun;84(6):607-18. doi: 10.1111/j.1360-0443.1989.tb03476.x.

DOI:10.1111/j.1360-0443.1989.tb03476.x
PMID:2787684
Abstract

A common strategy in epidemiological studies linking alcohol consumption in the general population with liver cirrhosis mortality is to use non-specific cirrhosis mortality rates in which alcoholic and non-alcoholic causes of death are not distinguished. Evidence is presented from Scottish mortality data for 1979 to 1984 that the two forms of cirrhosis have quite different epidemiological profiles. Similar findings emerge from morbidity data. The two forms of disease should be distinguished in future studies in which liver cirrhosis is used as a proxy for consumption, despite the manifest shortcomings of currently available data.

摘要

在将普通人群饮酒与肝硬化死亡率联系起来的流行病学研究中,一种常见策略是使用未区分酒精性和非酒精性死亡原因的非特异性肝硬化死亡率。从1979年至1984年苏格兰死亡率数据中可以看出,这两种形式的肝硬化具有截然不同的流行病学特征。发病率数据也得出了类似的结果。尽管现有数据存在明显缺陷,但在未来将肝硬化用作饮酒替代指标的研究中,应区分这两种形式的疾病。

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