Chijiwa T, Araki H, Ishibashi T, Inomata H
Department of Ophthalmology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Ophthalmologica. 1989;199(1):16-23. doi: 10.1159/000310008.
We examined ultrastructurally zonules of the lens obtained from a patient with exfoliation glaucoma and lens dislocation. There was a great accumulation of exfoliation materials adjacent to and within degenerated zonules, and a gradual transition between zonular fibrils and exfoliation materials was observed. The initial change in the zonular fibrils was a loss of their regularity, next we could see fine granules deposited on degenerated zonular fibrils. A sparse and irregular deposition was found on the surface of the fibrils. Subsequently, the deposition became increased, and densely stained exfoliation materials, which were composed of a single degenerated zonular fibril and fine granules, were formed. Several fibrils accompanied by fine granules clustered together and became exfoliation materials of larger diameter. These observations suggest that degenerated zonular fibrils may develop into exfoliation materials.
我们对一名剥脱性青光眼伴晶状体脱位患者的晶状体悬韧带进行了超微结构检查。在退变的悬韧带附近及内部有大量剥脱物质积聚,并且观察到悬韧带纤维与剥脱物质之间存在逐渐过渡。悬韧带纤维的初始变化是其规则性丧失,接下来我们可以看到细小颗粒沉积在退变的悬韧带纤维上。在纤维表面发现稀疏且不规则的沉积。随后,沉积增加,形成了由单个退变的悬韧带纤维和细小颗粒组成的深染剥脱物质。几条伴有细小颗粒的纤维聚集在一起,形成了直径更大的剥脱物质。这些观察结果表明,退变的悬韧带纤维可能发展为剥脱物质。