Zoologisches Institut, Zell und Neurobiologie, Karlsruhe Institute of Technology (KIT), Fritz-Haber-Weg 4, 76131, Karlsruhe, Germany.
Institut für Angewandte Physik, Karlsruhe Institute of Technology (KIT), Wolfgang-Gaede-Straße 1, 76131, Karlsruhe, Germany.
Adv Mater. 2017 Feb;29(5). doi: 10.1002/adma.201604342. Epub 2016 Nov 24.
The combination of three different photoresists into a single direct laser written 3D microscaffold permits functionalization with two bioactive full-length proteins. The cell-instructive microscaffolds consist of a passivating framework equipped with light activatable constituents featuring distinct protein-binding properties. This allows directed cell attachment of epithelial or fibroblast cells in 3D.
三种不同光致抗蚀剂的组合被用于单一的直接激光写入 3D 微支架中，这使得两种生物活性全长蛋白的功能化成为可能。这些具有细胞诱导性的微支架由一个具有钝化功能的框架组成，该框架配备了具有不同蛋白结合特性的光激活成分。这使得上皮细胞或成纤维细胞能够在 3D 中定向附着。
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