Lee M G, Terry S I, Raju K, Donaldson E K
West Indian Med J. 1989 Jun;38(2):75-9.
The results of oesophageal sclerotherapy (OS) in 18 patients with recurrent bleeding varices are compared with 15 patients treated medically. The total transfusion requirement pre-sclerotherapy was 112 units of blood (mean 6/patient) which decreased to 46 units (mean 2.5) after sclerotherapy treatment was started (p = 0.005). In the medically treated group, total transfusion was 74 units (mean 5 units/patient). One hundred and forty-three injection sclerotherapy sessions were given, and all but one patient had significant reduction or eradication of varices. Three patients died of recurrent bleeding (17%) and one other required surgery. In the medically treated group, 3 patients died of bleeding (20%). Complications of sclerotherapy included mild bleeding (39%), chest pain (28%) and oesophageal ulcer (5.5%). OS reduces transfusion requirements in patients with recurrent variceal bleeding.
对18例复发性静脉曲张出血患者进行食管硬化疗法(OS)的结果与15例接受药物治疗的患者进行了比较。硬化疗法前的总输血量为112单位血液(平均每位患者6单位),在开始硬化疗法治疗后降至46单位(平均2.5单位)(p = 0.005)。在药物治疗组中,总输血量为74单位(平均每位患者5单位)。共进行了143次注射硬化疗法,除1例患者外,所有患者的静脉曲张均显著减轻或消除。3例患者死于复发性出血(17%),另有1例需要手术治疗。在药物治疗组中,3例患者死于出血(20%)。硬化疗法的并发症包括轻度出血(39%)、胸痛(28%)和食管溃疡(5.5%)。食管硬化疗法可降低复发性静脉曲张出血患者的输血量需求。