Ekins Sean, Spektor Anna Coulon, Clark Alex M, Dole Krishna, Bunin Barry A
Collaborative Drug Discovery, Inc., 1633 Bayshore Highway, Suite 342, Burlingame, CA 94010, USA; Collaborations in Chemistry, Inc., 5616 Hilltop Needmore Road, Fuquay-Varina, NC 27526, USA.
Collaborative Drug Discovery, Inc., 1633 Bayshore Highway, Suite 342, Burlingame, CA 94010, USA.
Drug Discov Today. 2017 Mar;22(3):555-565. doi: 10.1016/j.drudis.2016.10.009. Epub 2016 Nov 22.
Neglected disease drug discovery is generally poorly funded compared with major diseases and hence there is an increasing focus on collaboration and precompetitive efforts such as public-private partnerships (PPPs). The More Medicines for Tuberculosis (MM4TB) project is one such collaboration funded by the EU with the goal of discovering new drugs for tuberculosis. Collaborative Drug Discovery has provided a commercial web-based platform called CDD Vault which is a hosted collaborative solution for securely sharing diverse chemistry and biology data. Using CDD Vault alongside other commercial and free cheminformatics tools has enabled support of this and other large collaborative projects, aiding drug discovery efforts and fostering collaboration. We will describe CDD's efforts in assisting with the MM4TB project.
与主要疾病相比,被忽视疾病的药物研发通常资金不足,因此人们越来越关注合作以及诸如公私伙伴关系(PPP)等竞争前的努力。“更多结核病药物”(MM4TB)项目就是欧盟资助的这样一个合作项目,其目标是发现治疗结核病的新药。协作药物发现公司提供了一个名为CDD Vault的基于网络的商业平台,它是一个托管的协作解决方案,用于安全地共享各种化学和生物学数据。将CDD Vault与其他商业和免费化学信息学工具一起使用,为该项目及其他大型合作项目提供了支持,有助于药物研发工作并促进合作。我们将描述CDD在协助MM4TB项目方面所做的努力。