Hirono I, Mori H, Haga M
J Natl Cancer Inst. 1978 Sep;61(3):865-9.
The carcinogenicity of Symphytum officinale L., Russian comfrey, used as a green vegetable or tonic, was studied in inbred ACI rats. Three groups of 19--28 rats each were fed comfrey leaves for 480--600 days; four additional groups of 15--24 rats were fed comfrey roots for varying lengths of time. A control group was given a normal diet. Hepatocellular adenomas were induced in all experimental groups that received the diets containing comfrey roots and leaves. Hemangioendothelial sarcoma of the liver was infrequently induced.
将聚合草（用作绿色蔬菜或滋补品）的致癌性在近交ACI大鼠中进行了研究。每组19 - 28只大鼠，共三组，喂食聚合草叶480 - 600天；另有四组，每组15 - 24只大鼠，喂食聚合草根不同时长。一组对照组给予正常饮食。所有接受含聚合草根和叶饮食的实验组均诱发了肝细胞腺瘤。肝血管内皮肉瘤很少诱发。
