通过延长储存时间或巴氏消毒法使寨卡病毒在人母乳中失活。
Inactivation of Zika virus in human breast milk by prolonged storage or pasteurization.
作者信息
Pfaender Stephanie, Vielle Nathalie J, Ebert Nadine, Steinmann Eike, Alves Marco P, Thiel Volker
机构信息
Department of Infectious Diseases and Pathobiology, University of Bern, Bern, Switzerland; Federal Department of Home Affairs, Institute of Virology and Immunology, Bern and Mittelhäusern, Switzerland.
Department of Infectious Diseases and Pathobiology, University of Bern, Bern, Switzerland; Federal Department of Home Affairs, Institute of Virology and Immunology, Bern and Mittelhäusern, Switzerland; Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland.
出版信息
Virus Res. 2017 Jan 15;228:58-60. doi: 10.1016/j.virusres.2016.11.025. Epub 2016 Nov 23.
Zika virus infection during pregnancy poses a serious risk for pregnant women as it can cause severe birth defects. Even though the virus is mainly transmitted via mosquitos, human-to-human transmission has been described. Infectious viral particles have been detected in breast milk of infected women which raised concerns regarding the safety of breastfeeding in areas of Zika virus transmission or in case of a suspected or confirmed Zika virus infection. In this study, we show that Zika virus is effectively inactivated in human breast milk after prolonged storage or upon pasteurization of milk.
孕期感染寨卡病毒对孕妇构成严重风险，因为它可导致严重的出生缺陷。尽管该病毒主要通过蚊子传播，但已有人际传播的报道。在感染女性的母乳中检测到了传染性病毒颗粒，这引发了人们对寨卡病毒传播地区或疑似或确诊寨卡病毒感染情况下母乳喂养安全性的担忧。在本研究中，我们表明，经过长时间储存或对母乳进行巴氏杀菌后，寨卡病毒能在人母乳中有效灭活。
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