Boido A, Vazzana I, Sparatore F, Cappello B, Diurno V, Matera C, Marrazzo R, Russo S, Cenicola M L, Marmo E
Istituto di Scienze Farmaceutiche, Università di Genova.
Farmaco. 1989 Mar;44(3):257-77.
A number of N-oxides of 4'-(benzotriazol-2-yl)-phenylalkanoic and -phenoxyalkanoic acids bearing various substituents on position 6 of benzotriazole together with 4'-(benzotriazol-2-yl) phenylacetic acid were prepared and subjected to a wide pharmacological screening. Several compounds exhibited significant antiinflammatory and diuretic activities, while one was endowed with antihypertensive activity.