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[Non-steroidal anti-inflammatory agents. III. Synthesis and analgesic-anti-inflammatory activity of 4-(pyrrol-1-yl)phenylacetamides and 4-(pyrrol-1-yl)phenethylamines].

作者信息

Stefancich G, Artico M, Corelli F, Massa S, Pantaleoni G C, Palumbo G, Fanini D, Giorgi G

出版信息

Farmaco Sci. 1984 Sep;39(9):752-64.

PMID:6333991
Abstract

Preparation of some 4-(pyrrol-1-yl)phenylacetamides and 4-(pyrrol-1-yl)phenylethylamines starting from 4-(pyrrol-1-yl)phenylacetic acid is reported. The new compounds were tested as analgesic-antiinflammatory agents. Data from pharmacological screening indicate 1-[4-(pyrrol-1-yl)phenylethyl]piperidine as the most active substance.

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