Hatori Nobuo, Sakai Hiroyuki, Sato Kazuyoshi, Miyajima Masayuki, Yuasa Shouhei, Kuboshima Shingo, Kajiwara Keiichi, Hara Yoshikuni, Minamizawa Kousuke, Miyakawa Masaaki
The Kanagawa Physicians Association.
J Nippon Med Sch. 2016;83(5):188-195. doi: 10.1272/jnms.83.188.
We performed a cross-sectional survey to investigate actual clinical practice concerning blood-pressure control among patients with hypertension in Kanagawa. The guidelines of the Japanese Society of Hypertension (JSH) for the management of patients with hypertension were revised in 2014. From October 1 to November 30, 2014, questionnaires on the care of patients with hypertension were sent via post to members of the Kanagawa Physicians Association in Kanagawa Prefecture, Japan. -Data on 1,105 patients (mean age: 68.4±12.3 years, 537 men and 568 women) were obtained. The overall mean systolic blood pressure (BP) of these patients was 128.7±12.1 mmHg for home monitoring and 132.9±12.6 mmHg for office monitoring; diastolic BP was 75.7±9.7 for home monitoring and 77.0±9.7 mmHg for office monitoring. According to the JSH 2014 guidelines, the target BP was achieved by 68.1% of all subjects; 89.2% of late-phase elderly patients (75 years or older); 69.1% of young, middle-aged, and early-phase elderly patients (younger than 75 years except in patients with diabetes mellitus [DM] or chronic kidney disease [CKD] with proteinuria); 9.3% of patients with DM except late-phase elderly patients; and 11.9% of CKD patients with proteinuria except DM. Cross-sectional analysis showed that the factors significantly associated with an increased likelihood of achieving the target BP were as follows: 1) good medication compliance even for a small number of antihypertensive agents at small amount of doses in patients 75 years and older; 2) good medication compliance in patients in younger than 75 years; 3) an older age, a larger proportion in the female-to-male ratio and a lower body mass index in patients with DM except late-phase elderly patients; and 4) usage of a large number of antihypertensive agents in CKD patients with proteinuria. Further follow-up surveys are necessary to investigate changes in clinical practice following the introduction of the revised guidelines.
我们开展了一项横断面调查,以研究神奈川县高血压患者血压控制的实际临床情况。日本高血压学会(JSH)高血压患者管理指南于2014年修订。2014年10月1日至11月30日,通过邮寄方式向日本神奈川县医师协会会员发送了高血压患者护理调查问卷。共获得了1105例患者的数据(平均年龄:68.4±12.3岁,男性537例,女性568例)。这些患者家庭自测收缩压总体平均值为128.7±12.1 mmHg,诊室测量收缩压总体平均值为132.9±12.6 mmHg;家庭自测舒张压为75.7±9.7 mmHg,诊室测量舒张压为77.0±9.7 mmHg。根据JSH 2014指南,所有受试者中有68.1%达到了目标血压;75岁及以上的老年晚期患者中达到目标血压的比例为89.2%;青年、中年及老年早期患者(75岁以下,糖尿病[DM]或慢性肾病[CKD]伴蛋白尿患者除外)中达到目标血压的比例为69.1%;DM患者(老年晚期患者除外)中达到目标血压的比例为9.3%;CKD伴蛋白尿患者(DM患者除外)中达到目标血压的比例为11.9%。横断面分析显示,与达到目标血压可能性增加显著相关的因素如下:1)75岁及以上患者即使服用少量降压药、小剂量也有良好的用药依从性;2)75岁以下患者有良好的用药依从性;3)DM患者(老年晚期患者除外)年龄较大、女性与男性比例较高且体重指数较低;4)CKD伴蛋白尿患者使用大量降压药。有必要进行进一步的随访调查,以研究修订指南引入后临床实践的变化。