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NUP98-fusion transcripts characterize different biological entities within acute myeloid leukemia: a report from the AIEOP-AML group.

作者信息

Bisio V, Zampini M, Tregnago C, Manara E, Salsi V, Di Meglio A, Masetti R, Togni M, Di Giacomo D, Minuzzo S, Leszl A, Zappavigna V, Rondelli R, Mecucci C, Pession A, Locatelli F, Basso G, Pigazzi M

机构信息

Dipartimento di Salute della Donna e del Bambino, Clinica di Oncoematologia Pediatrica, Università di Padova, Padova, Italy.

Istituto di Ricerca Pediatrica-Città della Speranza, Padova, Italy.

出版信息

Leukemia. 2017 Apr;31(4):974-977. doi: 10.1038/leu.2016.361. Epub 2016 Nov 28.

DOI:10.1038/leu.2016.361
PMID:27890935
Abstract
摘要

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NUP98-fusion transcripts characterize different biological entities within acute myeloid leukemia: a report from the AIEOP-AML group.NUP98融合转录本可表征急性髓系白血病中的不同生物学实体:来自AIEOP-AML组的报告。
Leukemia. 2017 Apr;31(4):974-977. doi: 10.1038/leu.2016.361. Epub 2016 Nov 28.
2
Acute leukemias and Burkitt's lymphoma. Present status of therapy.急性白血病和伯基特淋巴瘤。治疗现状。
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3
[Therapy of acute leukemia. Opinion of Prof. Franco Mandelli].[急性白血病的治疗。佛朗哥·曼德利教授的观点]
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4
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5
Combination chemotherapy in malignant diseases.恶性疾病的联合化疗
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Summary: recent advances in the treatment of acute leukemia and Burkitt's tumor.摘要:急性白血病和伯基特氏瘤治疗的最新进展。
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Frequency and prognostic impact of PAX5 p.P80R in pediatric acute lymphoblastic leukemia patients treated on an AIEOP-BFM acute lymphoblastic leukemia protocol.在接受 AIEOP-BFM 急性淋巴细胞白血病方案治疗的儿科急性淋巴细胞白血病患者中,PAX5 p.P80R 的频率及其对预后的影响。
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Minimal residual disease analysis in childhood mature B-cell leukaemia/lymphoma treated with AIEOP LNH-97 protocol with/without anti-CD20 administration.采用AIEOP LNH - 97方案治疗并接受或未接受抗CD20治疗的儿童成熟B细胞白血病/淋巴瘤的微小残留病分析
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本文引用的文献

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NUP98 is rearranged in 3.8% of pediatric AML forming a clinical and molecular homogenous group with a poor prognosis.NUP98 基因重排在 3.8% 的儿童急性髓系白血病中发生,形成了一个具有临床和分子均一性、预后不良的群组。
Leukemia. 2017 Mar;31(3):565-572. doi: 10.1038/leu.2016.267. Epub 2016 Oct 3.
2
Characterization of children with FLT3-ITD acute myeloid leukemia: a report from the AIEOP AML-2002 study group.FLT3-ITD 急性髓系白血病患儿的特征:来自 AIEOP AML-2002 研究组的报告。
Leukemia. 2017 Jan;31(1):18-25. doi: 10.1038/leu.2016.177. Epub 2016 Jun 28.
3
Small molecule inhibition of cAMP response element binding protein in human acute myeloid leukemia cells.
髓系恶性肿瘤中的NUP98致癌融合:分子机制与治疗机会的最新进展
Hemasphere. 2024 Sep 25;8(9):e70013. doi: 10.1002/hem3.70013. eCollection 2024 Sep.
4
NUP98 is rearranged in 5.0% of adult East Asian patients with AML.在5.0%的成年东亚急性髓系白血病患者中,核孔蛋白98(NUP98)发生重排。
Blood Adv. 2024 Oct 8;8(19):5122-5125. doi: 10.1182/bloodadvances.2024012960.
5
Clinical features and prognosis of patients with myeloid neoplasms harboring t(7;11)(p15;p15) translocation: a single-center retrospective study.伴有 t(7;11)(p15;p15) 易位的髓系肿瘤患者的临床特征和预后:一项单中心回顾性研究。
BMC Cancer. 2024 Aug 5;24(1):955. doi: 10.1186/s12885-024-12679-8.
6
Phase separation is regulated by post-translational modifications and participates in the developments of human diseases.相分离受翻译后修饰调控,并参与人类疾病的发生发展。
Heliyon. 2024 Jul 3;10(13):e34035. doi: 10.1016/j.heliyon.2024.e34035. eCollection 2024 Jul 15.
7
Combination of menin and kinase inhibitors as an effective treatment for leukemia with NUP98 translocations.联合使用 menin 和激酶抑制剂治疗 NUP98 易位白血病的有效方法。
Leukemia. 2024 Aug;38(8):1674-1687. doi: 10.1038/s41375-024-02312-9. Epub 2024 Jun 18.
8
Therapeutic targeting in pediatric acute myeloid leukemia with aberrant HOX/MEIS1 expression.治疗靶向治疗伴有异常 HOX/MEIS1 表达的小儿急性髓系白血病。
Eur J Med Genet. 2023 Dec;66(12):104869. doi: 10.1016/j.ejmg.2023.104869. Epub 2023 Oct 29.
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Blood. 2013 Jul 11;122(2):170-8. doi: 10.1182/blood-2013-03-491621. Epub 2013 May 14.
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Leukemia. 2013 Dec;27(12):2280-8. doi: 10.1038/leu.2013.87. Epub 2013 Mar 27.
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