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本文引用的文献

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The association of high-sensitivity c-reactive protein and other biomarkers with cardiovascular disease in patients treated for HIV: a nested case-control study.接受抗逆转录病毒治疗的HIV感染者中高敏C反应蛋白及其他生物标志物与心血管疾病的相关性：一项巢式病例对照研究
BMC Infect Dis. 2013 Sep 3;13:414. doi: 10.1186/1471-2334-13-414.
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Inflammation, coagulation and cardiovascular disease in HIV-infected individuals.HIV 感染者的炎症、凝血和心血管疾病。
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Change in high-sensitivity c-reactive protein levels following initiation of efavirenz-based antiretroviral regimens in HIV-infected individuals.在感染HIV的个体中，开始基于依非韦伦的抗逆转录病毒治疗方案后高敏C反应蛋白水平的变化。
AIDS Res Hum Retroviruses. 2011 May;27(5):461-8. doi: 10.1089/aid.2010.0154. Epub 2010 Nov 23.
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Traditional risk factors and D-dimer predict incident cardiovascular disease events in chronic HIV infection.传统风险因素和 D-二聚体可预测慢性 HIV 感染患者的心血管疾病事件。
AIDS. 2010 Jun 19;24(10):1509-17. doi: 10.1097/QAD.0b013e32833ad914.
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C-reactive protein levels increase during HIV-1 disease progression in Rakai, Uganda, despite the absence of microbial translocation.在乌干达拉凯，尽管没有微生物易位，但 C 反应蛋白水平在 HIV-1 疾病进展过程中会升高。
J Acquir Immune Defic Syndr. 2010 Aug;54(5):556-9. doi: 10.1097/QAI.0b013e3181e0cdea.
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Highly sensitive C-reactive protein, body mass index, and serum lipids in HIV-infected persons receiving antiretroviral therapy: a longitudinal study.接受抗逆转录病毒治疗的HIV感染者的高敏C反应蛋白、体重指数和血脂：一项纵向研究。
J Acquir Immune Defic Syndr. 2009 Dec 1;52(4):480-7. doi: 10.1097/qai.0b013e3181b939e5.
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SEROLOGICAL REACTIONS IN PNEUMONIA WITH A NON-PROTEIN SOMATIC FRACTION OF PNEUMOCOCCUS.非蛋白荚膜肺炎球菌部分引起肺炎的血清学反应。
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Cardiovascular risk assessment in antiretroviral-naïve HIV patients.初治HIV患者的心血管风险评估
AIDS Patient Care STDS. 2009 Oct;23(10):809-13. doi: 10.1089/apc.2009.0102.
9
Cytokine activation is predictive of mortality in Zambian patients with AIDS-related diarrhoea.细胞因子激活可预测赞比亚艾滋病相关腹泻患者的死亡率。
BMC Infect Dis. 2008 Nov 13;8:156. doi: 10.1186/1471-2334-8-156.
10
Endothelial function in human immunodeficiency virus-infected antiretroviral-naive subjects before and after starting potent antiretroviral therapy: The ACTG (AIDS Clinical Trials Group) Study 5152s.强效抗逆转录病毒治疗开始前后，未接受过抗逆转录病毒治疗的人类免疫缺陷病毒感染受试者的内皮功能：艾滋病临床试验组（ACTG）5152s研究
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高敏C反应蛋白检测在HIV患者中的作用。

Role of high-sensitivity C-reactive protein measurements in HIV patients.

作者信息

Vishwanath Arun, Quaiser Saif, Khan Ruhi

机构信息

Department of Medicine, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.

出版信息

Indian J Sex Transm Dis AIDS. 2016 Jul-Dec;37(2):123-128. doi: 10.4103/0253-7184.192127.

DOI:10.4103/0253-7184.192127
PMID:27890944
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5111295/
Abstract

As we herald into the 21 century, the quality of life and the repertoire of highly active antiretroviral therapy (HAART) have considerably improved. However, considerable work is still needed to educate the population about primary and secondary prevention modalities. Moreover, regular monitoring of immune response with patients on HAART with conventional biomarkers is still a problem in low resource settings which needs to be addressed. We aim to review high-sensitivity C-reactive protein as a potential biomarker in this regard.

摘要

随着我们迈入21世纪，生活质量和高效抗逆转录病毒疗法（HAART）的种类有了显著改善。然而，仍需要开展大量工作来对公众进行一级和二级预防方式的教育。此外，在资源匮乏地区，使用传统生物标志物对接受HAART治疗的患者进行免疫反应的定期监测仍是一个需要解决的问题。我们旨在综述高敏C反应蛋白在这方面作为一种潜在生物标志物的情况。