非蛋白荚膜肺炎球菌部分引起肺炎的血清学反应。
SEROLOGICAL REACTIONS IN PNEUMONIA WITH A NON-PROTEIN SOMATIC FRACTION OF PNEUMOCOCCUS.
机构信息
Hospital of The Rockefeller Institute for Medical Research.
出版信息
J Exp Med. 1930 Sep 30;52(4):561-71. doi: 10.1084/jem.52.4.561.
Abstract
- Sera from individuals acutely ill with lobar pneumonia possess the capacity to precipitate in high titre a non-protein somatic fraction derived from pneumococci (Fraction C). Following crisis the reaction is no longer demonstrable. 2. Sera obtained from cases of pneumococcus pneumonia during illness and convalescence have been tested for antibodies specifically reactive with three chemically distinct constituents of Pneumococcus. The results, when correlated with the course of disease, demonstrate differences in the occurrence of each qualitatively distinct antibody. 3. The precipitation of pneumococcus Fraction C is not limited to the sera of individuals ill with pneumococcus infection. But in the few other cases available for comparative tests, definite reactions have been obtained only in streptococcus and staphylococcus infections and in acute rheumatic fever.
摘要
患大叶性肺炎的个体的血清具有沉淀高滴度来自肺炎球菌的非蛋白体细胞部分（C 部分）的能力。危机过后，该反应不再可检测到。
从患病和恢复期的肺炎球菌肺炎病例中获得的血清已被检测出针对肺炎球菌三种化学上不同成分的特异性抗体。将这些结果与疾病的过程相关联，证明了每种定性独特抗体的发生存在差异。
肺炎球菌 C 部分的沉淀不仅限于患有肺炎球菌感染的个体的血清。但是，在其他几个可供比较测试的情况下，只有在链球菌和葡萄球菌感染以及急性风湿热中才获得了明确的反应。
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