• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一名感染人类免疫缺陷病毒的女童出现蛋白S和蛋白C缺乏伴多发梗死。

Protein S and protein C deficiency with multiple infarcts in a human immunodeficiency virus-infected female child.

作者信息

Shah Ira

机构信息

Department of Pediatric HIV, B.J. Wadia Hospital for Children, Parel, Mumbai, Maharashtra, India.

出版信息

Indian J Sex Transm Dis AIDS. 2016 Jul-Dec;37(2):190-192. doi: 10.4103/0253-7184.192119.

DOI:10.4103/0253-7184.192119
PMID:27890956
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5111307/
Abstract

Thrombotic episodes have occurred in patients with human immunodeficiency virus (HIV) infection, and various abnormalities leading to hypercoagulable state have been reported. However, multiple cerebral infarctions in an HIV-infected child along with protein S and protein C deficiency are rare. We report such a case in an antiretroviral therapy-naive HIV-infected female child.

摘要

血栓形成事件已发生在人类免疫缺陷病毒(HIV)感染患者中,并且已报道了导致高凝状态的各种异常情况。然而,一名感染HIV的儿童出现多发性脑梗死并伴有蛋白S和蛋白C缺乏的情况较为罕见。我们报告了一例从未接受过抗逆转录病毒治疗的感染HIV的女童出现这种情况的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d14e/5111307/6df4dba986c4/IJSTD-37-190-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d14e/5111307/aaa9669a5511/IJSTD-37-190-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d14e/5111307/6df4dba986c4/IJSTD-37-190-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d14e/5111307/aaa9669a5511/IJSTD-37-190-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d14e/5111307/6df4dba986c4/IJSTD-37-190-g002.jpg

相似文献

1
Protein S and protein C deficiency with multiple infarcts in a human immunodeficiency virus-infected female child.一名感染人类免疫缺陷病毒的女童出现蛋白S和蛋白C缺乏伴多发梗死。
Indian J Sex Transm Dis AIDS. 2016 Jul-Dec;37(2):190-192. doi: 10.4103/0253-7184.192119.
2
Acquired protein S deficiency in children infected with human immunodeficiency virus.
Pediatr Infect Dis J. 1996 Feb;15(2):106-11. doi: 10.1097/00006454-199602000-00003.
3
Stroke and cerebral infarcts in children infected with human immunodeficiency virus.
Arch Pediatr Adolesc Med. 1994 Sep;148(9):965-70. doi: 10.1001/archpedi.1994.02170090079015.
4
Low immunologic response to highly active antiretroviral therapy in naive vertically human immunodeficiency virus type 1-infected children with severe immunodeficiency.初治的严重免疫缺陷的垂直感染1型人类免疫缺陷病毒儿童对高效抗逆转录病毒疗法的免疫反应低下。
Pediatr Infect Dis J. 2006 Apr;25(4):365-8. doi: 10.1097/01.inf.0000207419.50016.5e.
5
Osteonecrosis of the hip (Legg-Calvé-Perthes disease) in human immunodeficiency virus-infected children.人类免疫缺陷病毒感染儿童的髋关节骨坏死(Legg-Calvé-Perthes病)
Pediatrics. 2002 May;109(5):E74-4. doi: 10.1542/peds.109.5.e74.
6
Treatment with highly active antiretroviral therapy in human immunodeficiency virus type 1-infected children is associated with a sustained effect on growth.对感染1型人类免疫缺陷病毒的儿童采用高效抗逆转录病毒疗法进行治疗,与对生长的持续影响相关。
Pediatrics. 2002 Feb;109(2):E25. doi: 10.1542/peds.109.2.e25.
7
Outcomes of human immunodeficiency virus-infected and -exposed children undergoing surgery--a prospective study.接受手术的人类免疫缺陷病毒感染及暴露儿童的结局——一项前瞻性研究。
J Pediatr Surg. 2009 Apr;44(4):681-7. doi: 10.1016/j.jpedsurg.2008.08.036.
8
Impact of protease inhibitor substitution with efavirenz in HIV-infected children: results of the First Pediatric Switch Study.用依非韦伦替代蛋白酶抑制剂对HIV感染儿童的影响:首次儿科换药研究结果
Pediatrics. 2003 Mar;111(3):e275-81. doi: 10.1542/peds.111.3.e275.
9
Prothrombotic state in HIV: A study on protein C, protein S, homocysteine and correlation with CD4 counts.
Indian J Med Microbiol. 2018 Apr-Jun;36(2):201-206. doi: 10.4103/ijmm.IJMM_15_414.
10
Induction of Heme Oxygenase-1 Deficiency and Associated Glutamate-Mediated Neurotoxicity Is a Highly Conserved HIV Phenotype of Chronic Macrophage Infection That Is Resistant to Antiretroviral Therapy.血红素加氧酶-1缺乏的诱导及相关谷氨酸介导的神经毒性是慢性巨噬细胞感染的一种高度保守的HIV表型,对抗逆转录病毒疗法具有抗性。
J Virol. 2015 Oct;89(20):10656-67. doi: 10.1128/JVI.01495-15. Epub 2015 Aug 12.

本文引用的文献

1
Antiphospholipid syndrome in a human immunodeficiency virus 1-infected child.一名感染人类免疫缺陷病毒1型儿童的抗磷脂综合征
Pediatr Infect Dis J. 2006 Feb;25(2):185-6. doi: 10.1097/01.inf.0000200140.04406.d0.
2
Thrombosis and a hypercoagulable state in HIV-infected patients.HIV感染患者的血栓形成与高凝状态
Clin Appl Thromb Hemost. 2004 Jul;10(3):277-80. doi: 10.1177/107602960401000311.
3
Venous thrombosis among patients with AIDS.艾滋病患者中的静脉血栓形成。
Clin Appl Thromb Hemost. 2004 Jan;10(1):19-25. doi: 10.1177/107602960401000104.
4
Acquired protein C and protein S deficiency in HIV-infected patients.
Clin Appl Thromb Hemost. 2003 Oct;9(4):325-31. doi: 10.1177/107602960300900408.
5
AIDS and thrombosis: retrospective study of 131 HIV-infected patients.艾滋病与血栓形成:对131例HIV感染患者的回顾性研究。
AIDS Patient Care STDS. 2001 Jun;15(6):311-20. doi: 10.1089/108729101750279687.
6
Acquired protein S deficiency in children infected with human immunodeficiency virus.
Pediatr Infect Dis J. 1996 Feb;15(2):106-11. doi: 10.1097/00006454-199602000-00003.