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[磁县食管癌病因的多因素逐步回归分析]

[Multiple stepwise regression analysis of etiological factors of esophageal cancer in Cixian county].

作者信息

Hou J

机构信息

Hebei Cancer Institute, Shijiazhuang.

出版信息

Zhonghua Zhong Liu Za Zhi. 1989 Jan;11(1):25-7.

PMID:2789130
Abstract

Cixian county, one of the high-risk counties of esophageal cancer in the world, has a standardized mortality of 142.19/10(5) population, 1969-1971. The incidence of esophageal cancer had dropped year by year from 1974 to 1982. The significance of the incidence tendency was studied. The results are highly significant (P less than 0.001). The causative factors of esophageal cancer including five independent variables: X1 (number of people taking sanitized water), X2 (number of people on pickled Chinese cabbage), X3 (annual output of fruit), X4 (annual output of fresh vegetable) and X5 (annual output of sweet potato) and one dependent variable Y (morbidity of esophageal cancer) were studied by correlative analysis and multiple stepwise regression. Three correlative factors (X1, X2, and X5) with significant effect on the esophageal cancer were selected from the five suspected factors. The result indicated that taking sanitized water, reducing the number of people on pickled Chinese cabbage, changing the structure of food and keeping the nutrient balance, might decrease the incidence of esophageal cancer.

摘要

磁县是世界食管癌高发县之一,1969 - 1971年标准化死亡率为142.19/10万人口。1974年至1982年食管癌发病率逐年下降。对发病率趋势的意义进行了研究。结果具有高度显著性(P<0.001)。通过相关分析和多元逐步回归研究了食管癌的致病因素,包括五个自变量:X1(饮用卫生水的人数)、X2(食用酸菜的人数)、X3(水果年产量)、X4(新鲜蔬菜年产量)和X5(红薯年产量)以及一个因变量Y(食管癌发病率)。从五个可疑因素中筛选出对食管癌有显著影响的三个相关因素(X1、X2和X5)。结果表明,饮用卫生水、减少食用酸菜的人数、改变食物结构和保持营养平衡,可能会降低食管癌的发病率。

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