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短期心率变异性在充血性心力衰竭检测中的表现

The Performance of Short-Term Heart Rate Variability in the Detection of Congestive Heart Failure.

作者信息

Lucena Fausto, Barros Allan Kardec, Ohnishi Noboru

机构信息

Universidade CEUMA, No. 100, 65903-093 Imperatriz, MA, Brazil; Laboratory for Biological Information Processing, Universidade Federal do Maranhão, S/N, São Luís, MA, Brazil.

Laboratory for Biological Information Processing, Universidade Federal do Maranhão, S/N, São Luís, MA, Brazil.

出版信息

Biomed Res Int. 2016;2016:1675785. doi: 10.1155/2016/1675785. Epub 2016 Nov 6.

Abstract

Congestive heart failure (CHF) is a cardiac disease associated with the decreasing capacity of the cardiac output. It has been shown that the CHF is the main cause of the cardiac death around the world. Some works proposed to discriminate CHF subjects from healthy subjects using either electrocardiogram (ECG) or heart rate variability (HRV) from long-term recordings. In this work, we propose an alternative framework to discriminate CHF from healthy subjects by using HRV short-term intervals based on 256 RR continuous samples. Our framework uses a matching pursuit algorithm based on Gabor functions. From the selected Gabor functions, we derived a set of features that are inputted into a hybrid framework which uses a genetic algorithm and -nearest neighbour classifier to select a subset of features that has the best classification performance. The performance of the framework is analyzed using both Fantasia and CHF database from Physionet archives which are, respectively, composed of 40 healthy volunteers and 29 subjects. From a set of nonstandard 16 features, the proposed framework reaches an overall accuracy of 100% with five features. Our results suggest that the application of hybrid frameworks whose classifier algorithms are based on genetic algorithms has outperformed well-known classifier methods.

摘要

充血性心力衰竭(CHF)是一种与心输出量下降相关的心脏疾病。研究表明,CHF是全球心脏死亡的主要原因。一些研究提出使用心电图(ECG)或长期记录中的心率变异性(HRV)来区分CHF患者和健康受试者。在这项研究中,我们提出了一种替代框架,通过基于256个RR连续样本的HRV短期间隔来区分CHF患者和健康受试者。我们的框架使用基于Gabor函数的匹配追踪算法。从选定的Gabor函数中,我们导出了一组特征,这些特征被输入到一个混合框架中,该框架使用遗传算法和最近邻分类器来选择具有最佳分类性能的特征子集。使用来自Physionet档案库的Fantasia和CHF数据库分析该框架的性能,这两个数据库分别由40名健康志愿者和29名受试者组成。从一组非标准的16个特征中,所提出的框架使用五个特征达到了100%的总体准确率。我们的结果表明,其分类算法基于遗传算法的混合框架的应用优于知名的分类方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4e0/5116360/5679bb59dc3a/BMRI2016-1675785.001.jpg

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