Abbasi Mohammad Reza, Ghazi Mirsaeed Seyedeh Masoumeh, Mohammad Alizadeh Amir Houshang
Shahid Behesti University of Medical Sciences, Taleghani Hospital, Parvaneh Ave, Tabnak Str, Evin ,Tehran, Iran. Email:
Asian Pac J Cancer Prev. 2016 Oct 1;17(10):4563-4566. doi: 10.22034/apjcp.2016.17.10.4563.
Background/Objective: The aim of this study was to perform a comparative evaluation of the yields of conventional brush cytology and brush cytology with negative pressure in the diagnosis of malignant biliary strictures. Methods: A total of 132 consecutive patients undergoing endoscopic were identified. Of these, 88.0 had brush cytology after ERCP and 44 were Brush cytology with negative pressure. Retrograde cholangiopancreatography (ERCP) including brush cytology and brush cytology with negative pressure in patients with biliary strictures between 2012-2015. Endoscopic retrograde cholangiography was performed with a standard videoduodenoscope Olympus TFJ 160-R (Olympus, Hamburg, Germany) and brush cytology with a Cook medical Double Lumen Biliary BrushTM (Cytology). Means and standard frequencies were used to calculate variables. Results: Positive results for malignancy were obtained in 22 of 88 patients (25%) by brush cytology and 31 of 44 patients (70.4 %) by brush cytology with negative pressure. Conclusions: Sensitivity of cytology sampling could be maximized by negative pressure during ERCP.
背景/目的：本研究旨在对传统刷检细胞学和负压刷检细胞学在恶性胆管狭窄诊断中的取材成功率进行比较评估。方法：共纳入132例连续接受内镜检查的患者。其中，88例在ERCP术后进行了刷检细胞学检查，44例进行了负压刷检细胞学检查。2012年至2015年间，对胆管狭窄患者进行逆行胰胆管造影（ERCP），包括刷检细胞学检查和负压刷检细胞学检查。使用标准的奥林巴斯TFJ 160-R电子十二指肠镜（奥林巴斯，德国汉堡）进行内镜逆行胆管造影，并使用库克医疗双腔胆管刷（细胞学）进行刷检细胞学检查。采用均值和标准频率计算变量。结果：88例患者中，22例（25%）通过刷检细胞学检查获得恶性结果阳性，44例患者中，31例（70.4%）通过负压刷检细胞学检查获得阳性结果。结论：ERCP过程中通过负压可使细胞学取材的敏感性最大化。
