Abedi Ghasem, Janbabai Ghasem, Moosazadeh Mahmood, Farshidi Fereshte, Amiri Mohammad, Khosravi Ahmad
Health Sciences Research Center, Mazandaran University of Medical Sciences, Sari. Email:
Asian Pac J Cancer Prev. 2016 Oct 1;17(10):4615-4621. doi: 10.22034/apjcp.2016.17.10.4615.
Background: There has not been a general estimation about survival rates of breast cancer cases in Iran. Therefore, the present study aimed to assess survival using a meta-analysis. Materials and Methods: International credible databases such as Scopus, Web of Science, PubMed, Science direct and Google Scholar and Iranian databases such as Magiran, Irandoc and SID, from 1997 to 2015 were searched. All articles covering survival rate of breast cancer were entered into the study without any limits. Quality assessment of the articles and data extraction were performed by two researchers using the modified STROBE checklist, which includes 12 questions. Articles with scores greater than 8 were included in the analysis. A limitation of this meta-analysis was different methods for presenting of results in the papers surveyed. Results: A total of 21 articles with a sample of 12,195 people were analyzed. The one-year, three-year, five-year and ten-year survival rates of breast cancer in Iran were estimated to be 95.8% (94.6-97.0), 82.4% (79.0-85.8), 69.5% (64.5-74.5), 58.1% (39.6-76.6), respectively. The most important factors affecting survival of breast cancer were age, number of lymph nodes involved, size of the tumor and the stage of the disease. Conclusion: The five- and ten- year survival rates in Iran are lower than in developed countries. Conducting breast cancer screening plan support (including regular clinical examination, mammography), public training and raising awareness should be helpful in facilitating early diagnosis and increasing survival rates for Iranian women.
伊朗尚未对乳腺癌病例的生存率进行总体评估。因此，本研究旨在通过荟萃分析评估生存率。材料与方法：检索了1997年至2015年期间的国际权威数据库，如Scopus、科学网、PubMed、科学Direct和谷歌学术，以及伊朗的数据库，如Magiran、伊朗文献数据库和SID。所有涉及乳腺癌生存率的文章均无限制地纳入研究。由两名研究人员使用修改后的STROBE清单（包括12个问题）对文章进行质量评估和数据提取。得分大于8分的文章纳入分析。本荟萃分析的一个局限性是所调查论文中呈现结果的方法不同。结果：共分析了21篇文章，样本量为12195人。伊朗乳腺癌的一年、三年、五年和十年生存率估计分别为95.8%（94.6 - 97.0）、82.4%（79.0 - 85.8）、69.5%（64.5 - 74.5）、58.1%（39.6 - 76.6）。影响乳腺癌生存的最重要因素是年龄、受累淋巴结数量、肿瘤大小和疾病分期。结论：伊朗的五年和十年生存率低于发达国家。开展乳腺癌筛查计划支持（包括定期临床检查、乳房X线摄影）、公众培训和提高认识应有助于促进早期诊断并提高伊朗女性的生存率。
