Singh Garima, Raghav Pankaja, Rustagi Neeti, Jaiswal Abhishek
Department of Community Medicine, Lady Hardinge Medical College, Delhi, IND.
Department of Community Medicine and Family Medicine, All India Institute of Medical Sciences, Jodhpur, Jodhpur, IND.
Cureus. 2024 May 9;16(5):e59990. doi: 10.7759/cureus.59990. eCollection 2024 May.
Background Cancer is the leading cause of death globally. Information on cancer patterns and survival is essential for the effective planning and implementation of cancer control interventions. Objective This study aimed to identify various factors associated with the survival estimates of common cancers. Methods A community-based ambispective study was conducted in a rural population. Data were collected from individuals diagnosed with cancer or relatives of individuals who died of cancer. The total population covered was 82,983. All cancer cases diagnosed since 2005 and followed until the year 2020 were included. Survival analysis and five-year survival rates were estimated. A Cox proportional hazard model was used. Results A total of 146 cancer patients were included in the study. Five-year survival estimates for breast cancer, head and neck cancer, and GI cancer were 72%, 28%, and 0%, respectively. The median survival time was lowest for GI cancers (1 year), and for head and neck and breast cancers, it was 3 and 6 years, respectively. Multivariate Cox regression was performed, adjusting for age, type of hospital, alcohol use, tobacco use, opium use, gender, treatment sought, GI cancer, frequency of changing hospitals, and frequency of follow-up. After adjustment, changing hospitals ≥3 times, being lost to follow-up, receiving no treatment, tobacco abuse, and the presence of GI cancers were significantly associated with survival estimates. Conclusions The five-year survival estimate for GI cancers was the lowest compared to other cancers. Study participants who were lost to follow-up or who took no treatment were significantly associated with lower survival estimates.
癌症是全球主要死因。癌症模式和生存率信息对于有效规划和实施癌症控制干预措施至关重要。目的：本研究旨在确定与常见癌症生存估计相关的各种因素。方法：在农村人口中开展了一项基于社区的回顾前瞻研究。数据收集自癌症确诊患者或死于癌症的患者亲属。覆盖的总人口为82,983人。纳入了自2005年以来确诊并随访至2020年的所有癌症病例。估计了生存分析和五年生存率。使用了Cox比例风险模型。结果：本研究共纳入146例癌症患者。乳腺癌、头颈癌和胃肠道癌的五年生存估计分别为72%、28%和0%。胃肠道癌的中位生存时间最短（1年），头颈癌和乳腺癌的中位生存时间分别为3年和6年。进行了多变量Cox回归分析，对年龄、医院类型、饮酒、吸烟、使用鸦片、性别、寻求的治疗、胃肠道癌、更换医院的频率和随访频率进行了调整。调整后，更换医院≥3次、失访、未接受治疗、吸烟和存在胃肠道癌与生存估计显著相关。结论：与其他癌症相比，胃肠道癌的五年生存估计最低。失访或未接受治疗的研究参与者与较低的生存估计显著相关。
