伴有甲下受累的大疱性坏疽性脓皮病与溃疡性结肠炎相关。

Bullous Pyoderma Gangrenosum With Subungual Involvement Associated With Ulcerative Colitis.

作者信息

Aktaş Karabay Ezgi, Aksu Cerman Aslı, Kıvanc Altunay İlknur, Yalçın Özben

机构信息

Departments of *Dermatology and Venereology, and †Clinical Pathology, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.

出版信息

Am J Dermatopathol. 2017 Jun;39(6):476-478. doi: 10.1097/DAD.0000000000000801.

DOI:10.1097/DAD.0000000000000801

PMID:27893467

Abstract

Pyoderma gangrenosum (PG) is a rare inflammatory and ulcerative skin disease of unknown etiology characterized by neutrophilic infiltration of the dermis, mainly affecting the lower extremities. Bullous PG is a rare variant of this disease, usually associated with hematologic disorders. Here, we report a case of pathergy-positive bullous PG with subungual involvement associated with ulcerative colitis.

摘要

坏疽性脓皮病（PG）是一种病因不明的罕见炎症性溃疡性皮肤病，其特征为真皮层嗜中性粒细胞浸润，主要累及下肢。大疱性PG是该疾病的一种罕见变体，通常与血液系统疾病相关。在此，我们报告一例伴有指（趾）甲下受累且与溃疡性结肠炎相关的同形反应阳性大疱性PG病例。