Redondo J, Latre J M, Torres M, Jiménez-Heffernan A, González F M, Llamas J M, Martínez M, Vallés F
Rev Esp Cardiol. 1989 Mar;42(3):162-8.
Stress and redistribution thallium-201 myocardial imaging using a transaxial single emission computed tomographic system has been applied to the diagnosis of coronary artery disease. Data sampling was performed along a limited 180 degree arc, obtaining 32 images in a continuous mode, at a rate of 20 seconds per image. The production of perfusion defects in patients was stimulated by exercise testing or by dipyridamole infusion. No significant differences existed when both tests were compared (p less than 0.01). Normal and abnormal patterns including the different pathophysiological alterations of myocardial ischemia were defined in three tomographic planes using this methodology. Patients with coronary disease are separated from patients without coronary disease with high probability (84%). Transaxial SPECT (single photon emission computerized tomography) provides a significant increment in sensitivity and specificity in relation to planar scintigraphy in the detection of myocardial infarction (91 and 100%, respectively); residual ischemia postinfarction (96 and 97%, respectively), and significant coronary artery disease (91 and 97%, respectively).
使用经轴单光子发射计算机断层扫描系统进行的应激及再分布铊-201心肌显像已应用于冠状动脉疾病的诊断。数据采样沿着有限的180度弧进行，以连续模式获取32幅图像，每幅图像的采集速率为20秒。通过运动试验或双嘧达莫输注来刺激患者灌注缺损的产生。比较这两种试验时未发现显著差异（p小于0.01）。使用该方法在三个断层平面中定义了包括心肌缺血不同病理生理改变的正常和异常模式。冠心病患者与无冠心病患者能够以较高概率（84%）区分开来。与平面闪烁显像相比，经轴单光子发射计算机断层扫描（SPECT）在检测心肌梗死（分别为91%和100%）、梗死后残余缺血（分别为96%和97%）以及严重冠状动脉疾病（分别为91%和97%）方面，敏感性和特异性均有显著提高。
