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运用血栓弹力图管理创伤性凝血病

Management of Trauma-Induced Coagulopathy with Thrombelastography.

作者信息

Gonzalez Eduardo, Moore Ernest E, Moore Hunter B

机构信息

Department of Surgery, University of Colorado, 12700 East 19th Avenue, Denver, CO 80045, USA.

Department of Surgery, University of Colorado, 12700 East 19th Avenue, Denver, CO 80045, USA; Department of Surgery, Denver Health Medical Center, 77 Bannock Street, Denver, CO 80204, USA; Editorial office, Journal of Trauma and Acute Care Surgery, 655 Broadway, Suite 365, Denver, CO 80203, USA.

出版信息

Crit Care Clin. 2017 Jan;33(1):119-134. doi: 10.1016/j.ccc.2016.09.002.

DOI:10.1016/j.ccc.2016.09.002
PMID:27894492
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5142763/
Abstract

Viscoelastic assays, such as thrombelastography (TEG) and rotational thrombelastometry (ROTEM), have emerged as point-of-care tools that can guide the hemostatic resuscitation of bleeding injured patients. This article describes the role of TEG in contemporary trauma care by explaining this assay's methodology, clinical applications, and result interpretation through description of supporting studies to provide the reader with an evidence-based user's guide. Although TEG and ROTEM are assays based on the same viscoelastic principle, this article is focused on data supporting the use of TEG in trauma, because it is available in trauma centers in North America; ROTEM is mostly available in Europe.

摘要

黏弹性检测,如血栓弹力图(TEG)和旋转血栓弹力测定法(ROTEM),已成为可指导出血受伤患者进行止血复苏的即时检测工具。本文通过解释该检测方法、临床应用以及通过对支持性研究的描述进行结果解读,来描述TEG在当代创伤护理中的作用,为读者提供一份基于证据的用户指南。尽管TEG和ROTEM是基于相同黏弹性原理的检测方法,但本文重点关注支持TEG在创伤中应用的数据,因为它在北美的创伤中心可用;ROTEM大多在欧洲可用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fde/5142763/21d1d38a6f5e/nihms-826421-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fde/5142763/5ba0a7726555/nihms-826421-f0001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fde/5142763/21d1d38a6f5e/nihms-826421-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fde/5142763/5ba0a7726555/nihms-826421-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fde/5142763/1a65deb33fb0/nihms-826421-f0002.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fde/5142763/21d1d38a6f5e/nihms-826421-f0004.jpg

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J Trauma Acute Care Surg. 2017 Jan;82(1):114-119. doi: 10.1097/TA.0000000000001270.
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Fatality and Severity of Firearm Injuries in a Denver Trauma Center, 2000-2013.2000 - 2013年丹佛创伤中心火器伤的死亡率和严重程度
JAMA. 2016 Jun 14;315(22):2465-7. doi: 10.1001/jama.2016.5978.
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Goal-directed Hemostatic Resuscitation of Trauma-induced Coagulopathy: A Pragmatic Randomized Clinical Trial Comparing a Viscoelastic Assay to Conventional Coagulation Assays.
黏弹性止血检测与多中心队列研究中的死亡率和输血相关。
J Am Coll Emerg Physicians Open. 2025 Jan 24;6(2):100042. doi: 10.1016/j.acepjo.2024.100042. eCollection 2025 Apr.
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ROTEM's utility in guiding resuscitation of traumatic lower extremity fracture patients.血栓弹力图(ROTEM)在指导创伤性下肢骨折患者复苏中的应用。
Arch Orthop Trauma Surg. 2025 Feb 25;145(1):170. doi: 10.1007/s00402-025-05773-4.
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Assessment of Bleeding in Acute Febrile Illness with Thrombocytopenia Using Thromboelastography and Conventional Coagulation Parameters in the Emergency Department (ABATE): A Prospective Cohort Study.急诊科使用血栓弹力图和传统凝血参数评估急性发热性疾病伴血小板减少症的出血情况(ABATE):一项前瞻性队列研究
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