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先天性凝血因子V缺乏症患者成功手术的围手术期血液管理

Perioperative Blood Management on a Successful Surgical Operation of a Patient With Congenital Coagulation Factor V Deficiency.

作者信息

Shi Ronghui, Wu Jianjun, Meng Qiang, Nie Ji, Zhang Li, Long Xiaoqiong, Yang Lan, Zhao Shuming

机构信息

Department of Blood Transfusion Guiqian International General Hospital Guiyang Guizhou China.

Department of Clinical Laboratory Guiqian International General Hospital Guiyang Guizhou China.

出版信息

Clin Case Rep. 2025 Sep 9;13(9):e70888. doi: 10.1002/ccr3.70888. eCollection 2025 Sep.

DOI:10.1002/ccr3.70888
PMID:40936679
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12420353/
Abstract

Thrombelastogram may provide a more accurate assessment of coagulation condition and transfusion strategy than the traditional coagulation profile and factor assays, and may be a useful ancillary tool guiding treatment decisions in factor V deficiency patients undergoing surgical procedures.

摘要

与传统凝血指标和因子检测相比，血栓弹力图可能能更准确地评估凝血状况和输血策略，并且可能是指导接受外科手术的Ⅴ因子缺乏症患者治疗决策的有用辅助工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a323/12420353/de6254cb155e/CCR3-13-e70888-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a323/12420353/4e7b4cba8e76/CCR3-13-e70888-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a323/12420353/de6254cb155e/CCR3-13-e70888-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a323/12420353/4e7b4cba8e76/CCR3-13-e70888-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a323/12420353/de6254cb155e/CCR3-13-e70888-g002.jpg

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本文引用的文献

1
EGFR-TKI-induced Factor V deficiency in a patient with advanced non-small cell lung cancer: The first case report.表皮生长因子受体酪氨酸激酶抑制剂致晚期非小细胞肺癌患者凝血因子 V 缺乏：首例报告
Lung Cancer. 2024 Aug;194:107869. doi: 10.1016/j.lungcan.2024.107869. Epub 2024 Jul 1.
2
A novel factor V compound heterozygous mutation associated with thrombosis (Y1961C; FV-Kanazawa, together with 1982_1983del).一种与血栓形成相关的新型因子 V 复合杂合突变（Y1961C；FV-Kanazawa，同时伴有 1982_1983del）。
J Thromb Haemost. 2024 Oct;22(10):2810-2822. doi: 10.1016/j.jtha.2024.06.014. Epub 2024 Jun 29.
3
Measurement of Blood Viscoelasticity Using Thromboelastography.
使用血栓弹力描记法测量血液粘弹性。
Methods Mol Biol. 2023;2663:709-724. doi: 10.1007/978-1-0716-3175-1_47.
4
Fatal acquired coagulation factor V deficiency after hepatectomy for advanced hepatocellular carcinoma as a possible immune checkpoint inhibitor-related adverse event: a case report.晚期肝细胞癌肝切除术后发生致命性获得性凝血因子V缺乏作为一种可能的免疫检查点抑制剂相关不良事件：一例报告
Surg Case Rep. 2023 Feb 2;9(1):16. doi: 10.1186/s40792-023-01601-2.
5
Laparoscopic hepatectomy for hepatocellular carcinoma in a patient with congenital factor V deficiency: a case report.先天性因子V缺乏患者的腹腔镜肝癌切除术：一例报告
Surg Case Rep. 2022 Oct 22;8(1):202. doi: 10.1186/s40792-022-01559-7.
6
Congenital coagulation factor V deficiency with intracranial hemorrhage.先天性凝血因子 V 缺乏伴颅内出血。
J Clin Lab Anal. 2022 Nov;36(11):e24705. doi: 10.1002/jcla.24705. Epub 2022 Sep 20.
7
Congenital factor V deficiency from compound heterozygous mutations with a novel variant c.2426del (p.Pro809Hisfs*2) in the F5 gene: A case report.F5基因复合杂合突变伴新变异c.2426del（p.Pro809Hisfs*2）导致的先天性因子V缺乏症：一例报告
Medicine (Baltimore). 2020 Jan;99(5):e18947. doi: 10.1097/MD.0000000000018947.
8
Perioperative Management of a Patient with Severe Factor V Deficiency Presenting with Chronic Subdural Hematoma: A Clinical Report.围手术期严重因子 V 缺乏症合并慢性硬脑膜下血肿患者的处理：临床报告。
World Neurosurg. 2019 Jul;127:409-413. doi: 10.1016/j.wneu.2019.04.080. Epub 2019 Apr 15.
9
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Blood Cells Mol Dis. 2018 Jul;71:5-10. doi: 10.1016/j.bcmd.2018.01.002. Epub 2018 Apr 5.
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Management of Trauma-Induced Coagulopathy with Thrombelastography.运用血栓弹力图管理创伤性凝血病
Crit Care Clin. 2017 Jan;33(1):119-134. doi: 10.1016/j.ccc.2016.09.002.