一只幼兔麻醉期间意外心脏死亡，与右心室心肌纤维脂肪替代有关。

Romanucci M, Defourny S V P, Massimini M, Valerii V, Arbuatti A, Giordano V, Bongiovanni L, Perrone C, Della Salda L

Faculty of Veterinary Medicine, University of Teramo, Loc. Piano D'Accio S.P. 18, Teramo, Italy.

J Comp Pathol. 2017 Jan;156(1):33-36. doi: 10.1016/j.jcpa.2016.10.008. Epub 2016 Nov 25.

A 6-month-old female pet rabbit was presented for routine ovariectomy. The pre-anaesthetic evaluation was unremarkable and no anaesthetic complications occurred during the procedure. However, at the end of the surgery, the rabbit suddenly showed acute bradycardia and cardiac death. Necropsy examination revealed marked dilation of the right ventricle, associated with diffuse thinning of the right ventricular free wall. Gross and histopathological findings were suggestive of a congenital dilated cardiomyopathy characterized by fibro-fatty replacement of the right ventricular myocardium. Similar myocardial lesions have not been previously described in rabbits, although they have been documented in myocardial diseases of man, dogs, cats, cattle, horses and chimpanzees.

一只6个月大的雌性宠物兔因常规卵巢切除术前来就诊。麻醉前评估无异常，手术过程中未发生麻醉并发症。然而，手术结束时，兔子突然出现急性心动过缓并心脏死亡。尸检发现右心室明显扩张，伴有右心室游离壁弥漫性变薄。大体和组织病理学检查结果提示为先天性扩张型心肌病，其特征为右心室心肌纤维脂肪替代。虽然在人类、犬、猫、牛、马和黑猩猩的心肌疾病中已有相关记录，但此前尚未在兔子身上描述过类似的心肌病变。