Subramaniam Karuna, Gill Jeevit, Slattery Patrick, Shastri Aditi, Mathalon Daniel H, Nagarajan Srikantan, Vinogradov Sophia
Department of Psychiatry, University of California San Francisco San Francisco, CA, USA.
Department of Radiology and Biomedical Imaging, University of California San Francisco San Francisco, CA, USA.
Front Hum Neurosci. 2016 Nov 15;10:581. doi: 10.3389/fnhum.2016.00581. eCollection 2016.
This study investigates the neural mechanisms of mood induced modulation of cognition, specifically, on reality monitoring abilities. Reality monitoring is the ability to accurately distinguish the source of self-generated information from externally-presented contextual information. When participants were in a positive mood, compared to a neutral mood, they significantly improved their source memory identification abilities, particularly for self-generated information. However, being in a negative mood had no effect on reality monitoring abilities. Additionally, when participants were in a positive mood state, they showed activation in several regions that predisposed them to perform better at reality monitoring. Specifically, positive mood induced activity within the medial prefrontal cortex (mPFC) and posterior cingulate cortex (PCC) was associated with improvements in subsequent identification of self-generated information, and positive mood induced activation within the striatum (putamen) facilitated better identification of externally-presented information. These findings indicate that regions within mPFC, PCC and striatum are sensitive to positive mood-cognition enhancing effects that enable participants to be better prepared for subsequent reality monitoring decision-making.
本研究调查了情绪诱导的认知调节的神经机制，具体而言，是对现实监测能力的影响。现实监测是指准确区分自我产生的信息来源与外部呈现的情境信息的能力。当参与者处于积极情绪状态时，与中性情绪相比，他们显著提高了源记忆识别能力，尤其是对于自我产生的信息。然而，处于消极情绪对现实监测能力没有影响。此外，当参与者处于积极情绪状态时，他们在几个区域表现出激活，这使他们在现实监测中表现得更好。具体来说，积极情绪在内侧前额叶皮质（mPFC）和后扣带回皮质（PCC）诱导的活动与随后自我产生信息识别能力的提高相关，而积极情绪在纹状体（壳核）诱导的激活促进了对外部呈现信息的更好识别。这些发现表明，mPFC、PCC和纹状体内的区域对积极情绪-认知增强效应敏感，这种效应使参与者能够为随后的现实监测决策做好更好的准备。
