腹内侧前额叶皮质对目标导向行为选择的贡献。

Contributions of the ventromedial prefrontal cortex to goal-directed action selection.

机构信息

Computation and Neural Systems, California Institute of Technology, Pasadena, CA 91125, USA.

出版信息

Ann N Y Acad Sci. 2011 Dec;1239:118-29. doi: 10.1111/j.1749-6632.2011.06290.x.

Abstract

In this article, it will be argued that one of the key contributions of the ventromedial prefrontal cortex (vmPFC) to goal-directed action selection lies both in retrieving the value of goals that are the putative outcomes of the decision process and in establishing a relative preference ranking for these goals by taking into account the value of each of the different goals under consideration in a given decision-making scenario. These goal-value signals are then suggested to be used as an input into the on-line computation of action values mediated by brain regions outside of the vmPFC, such as parts of the parietal cortex, supplementary motor cortex, and dorsal striatum. Collectively, these areas can be considered to be constituent elements of a multistage decision process whereby the values of different goals must first be represented and ranked before the value of different courses of action available for the pursuit of those goals can be computed.

摘要

在本文中,我们将论证,腹内侧前额叶皮层(vmPFC)对目标导向行为选择的一个关键贡献,既在于检索被认为是决策过程结果的目标的价值,也在于通过考虑给定决策情景下每个不同目标的价值,为这些目标建立相对偏好排序。然后,这些目标价值信号被建议作为腹侧前额叶皮层以外的大脑区域(如顶叶皮层、辅助运动皮层和背侧纹状体)介导的在线动作值计算的输入。这些区域可以被认为是一个多阶段决策过程的组成部分,在这个过程中,不同目标的价值必须首先被表示和排序,然后才能计算出追求这些目标的不同行动方案的价值。

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