Gholamkar Lida, Mowlavi Ali Asghar, Sadeghi Mahdi, Athari Mitra
Department of Medical Radiation Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Physics Department, Hakim Sabzevari University, Sabzevar, Iran; International Center for Theoretical Physics (ICTP), Associate Federation Scheme, Medical Physics Field, Trieste, Italy.
Iran J Radiol. 2016 Aug 1;13(4):e36484. doi: 10.5812/iranjradiol.36484. eCollection 2016 Oct.
X-ray mammography is one of the general methods for early detection of breast cancer. Since glandular tissue in the breast is sensitive to radiation and it increases the risk of cancer, the given dose to the patient is very important in mammography.
The aim of this study was to determine the average absorbed dose of X-ray radiation in the glandular tissue of the breast during mammography examinations as well as investigating factors that influence the mean glandular dose (MGD). One of the precise methods for determination of MGD absorbed by the breast is Monte Carlo simulation method which is widely used to assess the dose.
We studied some different X-ray sources and exposure factors that affect the MGD. "Midi-future" digital mammography system with amorphous-selenium detector was simulated using the Monte Carlo N-particle extended (MCNPX) code. Different anode/filter combinations such as tungsten/silver (W/Ag), tungsten/rhodium (W/Rh), and rhodium/aluminium (Rh/Al) were simulated in this study. The voltage of X-ray tube ranged from 24 kV to 32 kV with 2 kV intervals and the breast phantom thickness ranged from 3 to 8 cm, and glandular fraction g varied from 10% to 100%.
MGD was measured for different anode/filter combinations and the effects of changing tube voltage, phantom thickness, combination and glandular breast tissue on MGD were studied. As glandular g and X-ray tube voltage increased, the breast dose increased too, and the increase of breast phantom thickness led to the decrease of MGD. The obtained results for MGD were consistent with the result of Boone et al. that was previously reported.
By comparing the results, we saw that W/Rh anode/filter combination is the best choice in breast mammography imaging because of the lowest delivered dose in comparison with W/Ag and Rh/Al. Moreover, breast thickness and g value have significant effects on MGD.
乳腺X线摄影是早期发现乳腺癌的常用方法之一。由于乳腺中的腺组织对辐射敏感,会增加患癌风险,因此在乳腺摄影中给予患者的剂量非常重要。
本研究的目的是确定乳腺摄影检查期间乳腺腺组织中X射线辐射的平均吸收剂量,并研究影响平均腺体剂量(MGD)的因素。确定乳腺吸收的MGD的精确方法之一是蒙特卡罗模拟法,该方法广泛用于评估剂量。
我们研究了一些影响MGD的不同X射线源和曝光因素。使用蒙特卡罗N粒子扩展(MCNPX)代码模拟了带有非晶硒探测器的“Midi-future”数字乳腺摄影系统。本研究模拟了不同的阳极/滤过器组合,如钨/银(W/Ag)、钨/铑(W/Rh)和铑/铝(Rh/Al)。X射线管电压范围为24 kV至32 kV,间隔为2 kV,乳腺体模厚度范围为3至8 cm,腺体分数g从10%变化到100%。
测量了不同阳极/滤过器组合的MGD,并研究了管电压、体模厚度、组合和乳腺腺组织变化对MGD的影响。随着腺体g和X射线管电压的增加,乳腺剂量也增加,乳腺体模厚度的增加导致MGD降低。获得的MGD结果与之前报道的Boone等人的结果一致。
通过比较结果,我们发现W/Rh阳极/滤过器组合是乳腺摄影成像中的最佳选择,因为与W/Ag和Rh/Al相比,其输送剂量最低。此外,乳腺厚度和g值对MGD有显著影响。