Meyer Patricia Froes, da Silva Rodrigo Marcel Valentim, Oliveira Glenda, Tavares Maely Azevedo da Silva, Medeiros Melyssa Lima, Andrada Camila Procopio, Neto Luis Gonzaga de Araujo
Potiguar University (UnP), Laureate International Universities, 59054-180 Natal, RN, Brazil.
Case Rep Dermatol Med. 2016;2016:6052194. doi: 10.1155/2016/6052194. Epub 2016 Nov 8.
Cryolipolysis is a noninvasive technique of localized fat reduction. Controlled cold exposure is performed in the selective destruction of fat cells. The aim of this study was to investigate the effects of cryolipolysis on adipocytes elimination through histological and sonographic analyses. This study reports the case of a 46-year-old female patient, with complaint of localized abdominal fat and in the preoperative period of abdominoplasty. The patient was submitted to a single 60-minute application of cryolipolysis, temperature of -5°C, on the hypogastrium area, 5 cm below the umbilicus. To study the effects of this treatment, ultrasound images taken before the session and 7, 15, 30, and 45 days after the therapy were analysed. After the abdominoplasty, parts of the treated and the untreated withdrawn abdominal tissues were evaluated macro- and microscopically. In ultrasound images, as well as in macroscopic and histological analyses, significant adipocytes destruction was detected, with consequent fat layer reduction and integrity of areas that were adjacent to the treated tissue. The presence of fibrosis observed during therapy and acknowledged through performed analyses encourages further studies to clarify such finding.
冷冻溶脂术是一种局部减脂的非侵入性技术。通过控制冷暴露来选择性破坏脂肪细胞。本研究的目的是通过组织学和超声分析研究冷冻溶脂术对脂肪细胞消除的影响。本研究报告了一例46岁女性患者的病例，该患者主诉腹部局部脂肪堆积，正处于腹部整形术前阶段。患者在脐下5厘米的下腹部区域接受了一次60分钟、温度为-5°C的冷冻溶脂治疗。为研究该治疗的效果，分析了治疗前以及治疗后7天、15天、30天和45天拍摄的超声图像。腹部整形术后，对治疗部位和未治疗部位的取出腹部组织进行了宏观和微观评估。在超声图像以及宏观和组织学分析中，均检测到明显的脂肪细胞破坏，脂肪层随之减少，且治疗组织相邻区域保持完整。治疗期间观察到并通过分析确认的纤维化现象促使进一步研究以阐明这一发现。
