• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

使用无菌脱细胞真皮基质对基于植入物的即刻乳房重建并发症发生率的影响。

The Effect of Sterile Acellular Dermal Matrix Use on Complication Rates in Implant-Based Immediate Breast Reconstructions.

作者信息

Lee Jun Ho, Park Youngsoo, Choi Kyoung Wook, Chung Kyu-Jin, Kim Tae Gon, Kim Yong-Ha

机构信息

Department of Plastic and Reconstructive Surgery, Yeungnam University College of Medicine, Daegu, Korea.

出版信息

Arch Plast Surg. 2016 Nov;43(6):523-528. doi: 10.5999/aps.2016.43.6.523. Epub 2016 Nov 18.

DOI:10.5999/aps.2016.43.6.523
PMID:27896182
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5122540/
Abstract

BACKGROUND

The use of acellular dermal matrix (ADM) in implant-based immediate breast reconstruction has been increasing. The current ADMs available for breast reconstruction are offered as aseptic or sterile. No published studies have compared aseptic and sterile ADM in implant-based immediate breast reconstruction. The authors performed a retrospective study to evaluate the outcomes of aseptic versus sterile ADM in implant-based immediate breast reconstruction.

METHODS

Implant-based immediate breast reconstructions with ADM conducted between April 2013 and January 2016 were included. The patients were divided into 2 groups: the aseptic ADM (AlloDerm) group and the sterile ADM (MegaDerm) group. Archived records were reviewed for demographic data and postoperative complication types and frequencies. The complications included were infection, flap necrosis, capsular contracture, seroma, hematoma, and explantation for any cause.

RESULTS

Twenty patients were reconstructed with aseptic ADM, and 68 patients with sterile ADM. Rates of infection (15.0% vs. 10.3%), flap necrosis (5.0% vs. 7.4%), capsular contracture (20.0% vs. 14.7%), seroma (10.0% vs. 14.7%), hematoma (0% vs. 1.5%), and explantation (10.0% vs. 8.8%) were not significantly different in the 2 groups.

CONCLUSIONS

Sterile ADM did not provide better results regarding infectious complications than aseptic ADM in implant-based immediate breast reconstruction.

摘要

背景

脱细胞真皮基质（ADM）在基于植入物的即刻乳房重建中的应用一直在增加。目前可用于乳房重建的ADM有无菌和非无菌两种类型。尚无已发表的研究比较无菌和非无菌ADM在基于植入物的即刻乳房重建中的效果。作者进行了一项回顾性研究，以评估无菌与非无菌ADM在基于植入物的即刻乳房重建中的结果。

方法

纳入2013年4月至2016年1月期间采用ADM进行的基于植入物的即刻乳房重建病例。患者分为两组：非无菌ADM（AlloDerm）组和无菌ADM（MegaDerm）组。查阅存档记录以获取人口统计学数据以及术后并发症的类型和发生率。所包括的并发症有感染、皮瓣坏死、包膜挛缩、血清肿、血肿以及因任何原因进行的假体取出。

结果

20例患者采用非无菌ADM进行重建，68例患者采用无菌ADM进行重建。两组在感染率（15.0%对10.3%）、皮瓣坏死率（5.0%对7.4%）、包膜挛缩率（20.0%对14.7%）、血清肿发生率（10.0%对14.7%）、血肿发生率（0%对1.5%）以及假体取出率（10.0%对8.8%）方面无显著差异。

结论

在基于植入物的即刻乳房重建中，无菌ADM在感染性并发症方面并未比非无菌ADM取得更好的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73b7/5122540/12fa88492e42/aps-43-523-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73b7/5122540/7ec950488152/aps-43-523-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73b7/5122540/e6a4931d7be9/aps-43-523-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73b7/5122540/12fa88492e42/aps-43-523-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73b7/5122540/7ec950488152/aps-43-523-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73b7/5122540/e6a4931d7be9/aps-43-523-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73b7/5122540/12fa88492e42/aps-43-523-g003.jpg

相似文献

1
The Effect of Sterile Acellular Dermal Matrix Use on Complication Rates in Implant-Based Immediate Breast Reconstructions.使用无菌脱细胞真皮基质对基于植入物的即刻乳房重建并发症发生率的影响。
Arch Plast Surg. 2016 Nov;43(6):523-528. doi: 10.5999/aps.2016.43.6.523. Epub 2016 Nov 18.
2
Sterile "ready-to-use" AlloDerm decreases postoperative infectious complications in patients undergoing immediate implant-based breast reconstruction with acellular dermal matrix.使用无菌的“即用型”同种异体真皮移植物可降低脱细胞真皮基质即刻乳房重建患者的术后感染并发症。
Plast Reconstr Surg. 2013 Oct;132(4):725-736. doi: 10.1097/PRS.0b013e31829fe35b.
3
Comparison of sterile versus nonsterile acellular dermal matrices for breast reconstruction.用于乳房重建的无菌与非无菌脱细胞真皮基质的比较。
Ann Plast Surg. 2013 May;70(5):497-9. doi: 10.1097/SAP.0b013e31827f52c8.
4
Reducing postoperative infections and red breast syndrome in patients with acellular dermal matrix-based breast reconstruction: the relative roles of product sterility and lower body mass index.降低基于脱细胞真皮基质的乳房重建患者术后感染和红胸综合征的发生率：产品无菌性和较低体重指数的相对作用
Ann Plast Surg. 2015 May;74 Suppl 1:S30-2. doi: 10.1097/SAP.0000000000000475.
5
Immediate Implant-Based Breast Reconstruction with Acellular Dermal Matrix: A Comparison of Sterile and Aseptic AlloDerm in 2039 Consecutive Cases.即刻基于假体的乳房重建应用脱细胞真皮基质：2039 例连续病例中无菌与消毒同种异体真皮的比较。
Plast Reconstr Surg. 2018 Dec;142(6):1401-1409. doi: 10.1097/PRS.0000000000004968.
6
A comparison of clinical outcomes of acellular dermal matrix with and without radiation sterilization process in immediate prepectoral direct-to-implant breast reconstruction.脱细胞真皮基质在即刻胸肌前置直接植入式乳房重建中应用于与不应用于辐射灭菌过程的临床结果比较。
J Plast Reconstr Aesthet Surg. 2023 Dec;87:461-466. doi: 10.1016/j.bjps.2023.10.087. Epub 2023 Oct 13.
7
A systematic review and meta-analysis of complications associated with acellular dermal matrix-assisted breast reconstruction.脱细胞真皮基质辅助乳房重建相关并发症的系统评价与荟萃分析
Ann Plast Surg. 2012 Apr;68(4):346-56. doi: 10.1097/SAP.0b013e31823f3cd9.
8
Comparison of Human, Porcine, and Bovine Acellular Dermal Matrix in Prepectoral Breast Reconstruction: A Scoping Review.人、猪和牛脱细胞真皮基质在前胸乳房重建中的比较：一项范围综述
Ann Plast Surg. 2022 Dec 1;89(6):694-702. doi: 10.1097/SAP.0000000000003319.
9
Aseptic versus Sterile Acellular Dermal Matrices in Breast Reconstruction: An Updated Review.乳房重建中无菌与灭菌脱细胞真皮基质：最新综述
Plast Reconstr Surg Glob Open. 2016 Jul 22;4(7):e823. doi: 10.1097/GOX.0000000000000819. eCollection 2016 Jul.
10
Breast reconstruction and revision surgery for implant-associated breast deformities using porcine acellular dermal matrix: a multicenter study of 156 cases.使用猪脱细胞真皮基质进行乳房重建及植入物相关乳房畸形修复手术：156例多中心研究
Ann Surg Oncol. 2015 Apr;22(4):1146-52. doi: 10.1245/s10434-014-4098-3. Epub 2014 Oct 10.

引用本文的文献

1
Effect of acellular dermal matrix thickness and surface area on direct-to-implant breast reconstruction.脱细胞真皮基质厚度和表面积对直接植入式乳房重建的影响。
Gland Surg. 2022 Aug;11(8):1301-1308. doi: 10.21037/gs-22-175.
2
Usefulness of Allogenic Acellular Dermal Matrix for Prevention of Scalp Depression after Burr Hole Trephination.同种异体脱细胞真皮基质在预防颅骨钻孔引流术后头皮凹陷中的应用价值。
Korean J Neurotrauma. 2020 Oct 7;16(2):174-180. doi: 10.13004/kjnt.2020.16.e34. eCollection 2020 Oct.
3
Intraoperative Autoderm Decontamination for Use in Immediate Single-stage Direct-to-implant Breast Reconstruction.

本文引用的文献

1
Characterization and tissue incorporation of cross-linked human acellular dermal matrix.交联人脱细胞真皮基质的表征和组织整合。
Biomaterials. 2015 Mar;44:195-205. doi: 10.1016/j.biomaterials.2014.12.004. Epub 2015 Jan 14.
2
Comparison between Freeze-dried and Ready-to-use AlloDerm in Alloplastic Breast Reconstruction.冻干异体真皮与即用型异体真皮在乳房假体再造中的比较。
Plast Reconstr Surg Glob Open. 2014 Apr 7;2(3):e119. doi: 10.1097/GOX.0000000000000061. eCollection 2014 Mar.
3
Sterile "ready-to-use" AlloDerm decreases postoperative infectious complications in patients undergoing immediate implant-based breast reconstruction with acellular dermal matrix.
术中自体皮肤去污用于即刻单阶段直接植入式乳房重建。
Plast Reconstr Surg Glob Open. 2020 Jul 15;8(7):e2968. doi: 10.1097/GOX.0000000000002968. eCollection 2020 Jul.
4
A comparative study between sterile freeze-dried and sterile pre-hydrated acellular dermal matrix in tissue expander/implant breast reconstruction.组织扩张器/植入物乳房重建中无菌冻干脱细胞真皮基质与无菌预水化脱细胞真皮基质的比较研究。
Arch Plast Surg. 2019 May;46(3):204-213. doi: 10.5999/aps.2018.01137. Epub 2019 May 15.
5
Surgical outcomes of tympanoplasty using a sterile acellular dermal allograft: a prospective randomised controlled study.使用无菌去细胞真皮移植物的鼓室成形术的手术结果：一项前瞻性随机对照研究。
Acta Otorhinolaryngol Ital. 2018 Dec;38(6):554-562. doi: 10.14639/0392-100X-1839.
6
Acellular dermal matrix in premature ejaculation: A preliminary study.脱细胞真皮基质治疗早泄的初步研究。
Medicine (Baltimore). 2018 Nov;97(45):e13135. doi: 10.1097/MD.0000000000013135.
7
A Breast Reconstruction Using a Breast Prosthesis and Capsular Flap for a Lymphocele Patient.使用乳房假体和包膜皮瓣对一名淋巴囊肿患者进行乳房重建。
Plast Reconstr Surg Glob Open. 2017 Oct 24;5(10):e1534. doi: 10.1097/GOX.0000000000001534. eCollection 2017 Oct.
8
Comparative Study of Prepectoral and Subpectoral Expander-Based Breast Reconstruction and Clavien IIIb Score Outcomes.基于胸大肌前和胸大肌下扩张器的乳房重建与Clavien IIIb评分结果的对比研究
Plast Reconstr Surg Glob Open. 2017 Jul 26;5(7):e1433. doi: 10.1097/GOX.0000000000001433. eCollection 2017 Jul.
使用无菌的“即用型”同种异体真皮移植物可降低脱细胞真皮基质即刻乳房重建患者的术后感染并发症。
Plast Reconstr Surg. 2013 Oct;132(4):725-736. doi: 10.1097/PRS.0b013e31829fe35b.
4
Comparison of sterile versus nonsterile acellular dermal matrices for breast reconstruction.用于乳房重建的无菌与非无菌脱细胞真皮基质的比较。
Ann Plast Surg. 2013 May;70(5):497-9. doi: 10.1097/SAP.0b013e31827f52c8.
5
Evaluating sterile human acellular dermal matrix in immediate expander-based breast reconstruction: a multicenter, prospective, cohort study.评价基于扩张器的即刻乳房重建中使用的无菌人脱细胞真皮基质：一项多中心、前瞻性、队列研究。
Plast Reconstr Surg. 2013 Jan;131(1):9e-18e. doi: 10.1097/PRS.0b013e3182729d4f.
6
Direct-to-implant breast reconstruction.直接向植入物乳房重建。
Clin Plast Surg. 2012 Apr;39(2):119-126. doi: 10.1016/j.cps.2012.01.001.
7
Comparison of implant-based immediate breast reconstruction with and without acellular dermal matrix.带与不带脱细胞真皮基质的基于植入物的即刻乳房重建的比较。
Plast Reconstr Surg. 2011 Nov;128(5):403e-410e. doi: 10.1097/PRS.0b013e31822b6637.
8
Use of human acellular dermal matrix in implant- based breast reconstruction: evaluating the evidence.在基于植入物的乳房重建中使用人脱细胞真皮基质：评估证据。
J Plast Reconstr Aesthet Surg. 2011 Dec;64(12):1553-61. doi: 10.1016/j.bjps.2011.02.001. Epub 2011 Mar 8.
9
Postoperative complications in prosthesis-based breast reconstruction using acellular dermal matrix.假体乳房再造术中使用脱细胞真皮基质的术后并发症。
Plast Reconstr Surg. 2011 May;127(5):1755-1762. doi: 10.1097/PRS.0b013e31820cf233.
10
Acellular human dermis implantation in 153 immediate two-stage tissue expander breast reconstructions: determining the incidence and significant predictors of complications.153 例即刻二期组织扩张器乳房重建中应用脱细胞人真皮植入物：确定并发症的发生率和显著预测因素。
Plast Reconstr Surg. 2010 Jun;125(6):1606-1614. doi: 10.1097/PRS.0b013e3181d4fb2a.