Gulacti Umut, Lok Ugur
Department of Emergency Medicine, Adiyaman University Medical Faculty, Adiyaman, Turkey.
Turk J Emerg Med. 2016 Apr 19;16(2):47-52. doi: 10.1016/j.tjem.2016.03.003. eCollection 2016 Jun.
The aim of the study is to determine factors affecting the return of spontaneous circulation (ROSC) ratios, neurological outcomes at discharge, the ratio of living patients discharged from the hospital and due to Do not attempt resuscitation (DNAR) prohibition.
This is a retrospective observational study conducted on patients of cardiopulmonary resuscitation (CPR) performed in emergency department (ED) and intensive care units between February 2010 and February 2012.
A total of 469 patients were evaluated, and 266 eligible patients who did not have DNAR orders were included in the study. Overall, 45.1% of the adult in-hospital cardiac arrest victims returned to spontaneous circulation, and 5.3% survived to hospital discharge. Of the patients who were discharged alive from the hospital, 33.3% were discharged in poor neurologic conditions of Cerebral Performance Category (CPC) score 3 or 4. The ROSC ratio was reduced for the patients with malignancies compared to the patients with other preexisting conditions (OR: 12.783; 95% CI 2.967-55.072; p = 0.000). None of the patients with malignancies were discharged alive from the hospital. Only one patient with end-stage disease was discharged alive from hospital, and this patient's CPC score was 4.
CPR has not increased the ROSC and alive discharge rates in patients with malignancy and end-state disease. DNAR order prohibition have been increased the futile CPR attempts. DNAR should be accepted as a human right that represents an honorable death option and whether a DNAR is order demanded should be specifically discussed with patients with malignancies and end-stage disease presenting to ED.
本研究旨在确定影响自主循环恢复(ROSC)率、出院时神经功能结局、出院存活患者比例以及因不进行心肺复苏(DNAR)禁令的因素。
这是一项回顾性观察研究,对2010年2月至2012年2月在急诊科(ED)和重症监护病房进行心肺复苏(CPR)的患者进行。
共评估了469例患者,266例无DNAR医嘱的合格患者纳入研究。总体而言,45.1%的成年住院心脏骤停患者恢复自主循环,5.3%存活至出院。在出院存活的患者中,33.3%出院时神经功能状态较差,脑功能分类(CPC)评分为3或4分。与其他基础疾病患者相比,恶性肿瘤患者的ROSC率降低(OR:12.783;95%CI 2.967 - 55.072;p = 0.000)。恶性肿瘤患者无一例出院存活。仅1例终末期疾病患者出院存活,该患者的CPC评分为4分。
CPR未提高恶性肿瘤和终末期疾病患者的ROSC率和存活出院率。DNAR禁令增加了无效的CPR尝试。DNAR应被视为一项人权,代表一种体面的死亡选择,对于就诊于ED的恶性肿瘤和终末期疾病患者,应专门讨论是否需要下达DNAR医嘱。