Baqi Abdul, Waheed Shahan, Tipoo Fateh Ali, Khan Aamir Hameed
Department of Cardiology, Aga Khan University Hospital, Pakistan.
Department of Emergency Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Turk J Emerg Med. 2016 May 8;16(2):83-85. doi: 10.1016/j.tjem.2015.05.002. eCollection 2016 Jun.
A 48 years old male presented to clinic with 12 months of low grade fever with shortness of breath which has progressively worsened with no associated weight loss, night sweats or loss of appetite. There was no prior history of chronic illness before the current illness. Laboratory workup revealed a high white blood cell count with predominant eosinophils. Chest X-ray was normal. Transthoracic echocardiography and Cardiac Magnetic Resonance showed biventricular thrombi. On further extensive workup the findings were consistent with hypereosinophilic syndrome. The patient was started on oral steroids, hydroxyurea, imatanib mesylate and oral anticoagulation. The patient responded to the treatment with complete resolution of his symptoms over the course of few months. The repeat Echocardiogram after a year showed normal left ventricular systolic and diastolic function with complete resolution of biventricular thrombi.
一名48岁男性因持续12个月的低热伴呼吸急促前来就诊，症状逐渐加重，无体重减轻、盗汗或食欲减退。本次发病前无慢性疾病史。实验室检查显示白细胞计数升高，以嗜酸性粒细胞为主。胸部X线检查正常。经胸超声心动图和心脏磁共振成像显示双心室血栓。进一步详细检查发现符合高嗜酸性粒细胞综合征。患者开始接受口服类固醇、羟基脲、甲磺酸伊马替尼和口服抗凝治疗。患者对治疗有反应，症状在几个月内完全缓解。一年后复查超声心动图显示左心室收缩和舒张功能正常，双心室血栓完全消失。
