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[体外二氧化碳清除作为拔管失败患者气管切开术的替代方法]

[Extracorporeal CO removal as an alternative to tracheotomy in a patient with extubation failure].

作者信息

Redel A, Ritzka M, Kraus S, Philipp A, Schlitt H-J, Graf B, Bein T

机构信息

Klinik für Anästhesiologie, Universitätsklinikum Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Deutschland.

Klinik für Chirurgie, Universitätsklinikum Regensburg, Regensburg, Deutschland.

出版信息

Anaesthesist. 2016 Dec;65(12):925-928. doi: 10.1007/s00101-016-0244-6. Epub 2016 Nov 28.

DOI:10.1007/s00101-016-0244-6
PMID:27896375
Abstract

We report a patient with chest trauma who was admitted to the ICU after surgery. As he fulfilled protocol-based criteria, he was extubated 7 days after admission. However, despite intermittent non-invasive ventilation, the patient had to be re-intubated on day 10 owing to progressive hypercapnia. We decided to support the patient with a mid-flow veno-venous extracorporeal carbon dioxide removal (ECCO‑R) system instead of a tracheotomy. Sufficient CO removal was established with a blood flow of 1.5 l/min and the patient was successfully extubated within a few hours. After 5 days of ECCO‑R the patient could be weaned and transferred to a general ward in a stable condition.

摘要

我们报告了一名胸部创伤患者,术后入住重症监护病房(ICU)。由于他符合基于方案的标准,入院7天后拔管。然而,尽管进行了间歇性无创通气,但患者在第10天因进行性高碳酸血症不得不再次插管。我们决定用中流量静脉-静脉体外二氧化碳清除(ECCO-R)系统支持该患者,而不是进行气管切开术。以1.5升/分钟的血流量实现了充分的二氧化碳清除,患者在数小时内成功拔管。经过5天的ECCO-R治疗,患者可以撤机并以稳定状态转至普通病房。

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本文引用的文献

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Venovenous extracorporeal membrane oxygenation for acute respiratory failure : A clinical review from an international group of experts.静脉-静脉体外膜肺氧合治疗急性呼吸衰竭:国际专家组的临床综述。
Intensive Care Med. 2016 May;42(5):712-724. doi: 10.1007/s00134-016-4314-7. Epub 2016 Mar 23.
2
Effects of Extracorporeal CO2 Removal on Inspiratory Effort and Respiratory Pattern in Patients Who Fail Weaning from Mechanical Ventilation.体外二氧化碳清除对机械通气撤机失败患者吸气努力和呼吸模式的影响。
Am J Respir Crit Care Med. 2015 Dec 1;192(11):1392-4. doi: 10.1164/rccm.201505-0930LE.
3
Long-term survival of critically ill patients treated with prolonged mechanical ventilation: a systematic review and meta-analysis.
接受长时间机械通气治疗的危重症患者的长期生存:系统评价和荟萃分析。
Lancet Respir Med. 2015 Jul;3(7):544-53. doi: 10.1016/S2213-2600(15)00150-2. Epub 2015 May 20.
4
Discontinuation of ventilatory support: new solutions to old dilemmas.停止通气支持:解决旧困境的新方法。
Curr Opin Crit Care. 2015 Feb;21(1):74-81. doi: 10.1097/MCC.0000000000000169.
5
Effect of early tracheostomy on resource utilization and clinical outcomes in critically ill patients: meta-analysis of randomized controlled trials.早期气管切开术对危重症患者资源利用和临床结局的影响:随机对照试验的荟萃分析。
Br J Anaesth. 2015 Mar;114(3):396-405. doi: 10.1093/bja/aeu440. Epub 2014 Dec 22.
6
Venovenous extracorporeal CO2 removal for early extubation in COPD exacerbations requiring invasive mechanical ventilation.在需要有创机械通气的慢性阻塞性肺疾病急性加重期患者中,采用静脉-静脉体外二氧化碳清除技术以实现早期拔管
Intensive Care Med. 2014 Dec;40(12):1969-70. doi: 10.1007/s00134-014-3503-5. Epub 2014 Sep 30.
7
First experience with a new miniaturized pump-driven venovenous extracorporeal CO2 removal system (iLA Activve): a retrospective data analysis.新型小型泵驱动静脉-静脉体外二氧化碳清除系统(iLA Activve)的首次使用经验:一项回顾性数据分析
ASAIO J. 2014 May-Jun;60(3):342-7. doi: 10.1097/MAT.0000000000000073.
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Effect of early vs late tracheostomy placement on survival in patients receiving mechanical ventilation: the TracMan randomized trial.早期与晚期气管切开术对机械通气患者生存影响的随机对照试验(TracMan 研究)
JAMA. 2013 May 22;309(20):2121-9. doi: 10.1001/jama.2013.5154.
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Lower tidal volume strategy (≈3 ml/kg) combined with extracorporeal CO2 removal versus 'conventional' protective ventilation (6 ml/kg) in severe ARDS: the prospective randomized Xtravent-study.低潮气量策略(≈3 ml/kg)联合体外 CO2 清除与严重 ARDS 中的“常规”保护性通气(6 ml/kg):前瞻性随机 Xtravent 研究。
Intensive Care Med. 2013 May;39(5):847-56. doi: 10.1007/s00134-012-2787-6. Epub 2013 Jan 10.
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