Drosos A A, Angelopoulos N V, Liakos A, Moutsopoulos H M
Department of Internal Medicine, Medical School, University of Ioannina, Greece.
J Autoimmun. 1989 Aug;2(4):489-93. doi: 10.1016/0896-8411(89)90180-7.
It has been recently suggested that primary Sjögren's syndrome (SS) patients present with a variety of personality structure disturbances and psychiatric symptoms. To evaluate this finding further, we assessed hostility structure and psychiatric symptoms in 33 Sjögren's syndrome patients and compared the results with those of 33 healthy women, and 41 women with solid malignant tumors. The utilized psychometric instruments were the hostility and direction of hostility questionnaire (HDHQ) and the symptom checklist 90R (SCL-90R). High levels of introverted hostility were reported by SS patients in relation to the other two groups. Cancer and SS patients reported higher scores on anxiety and depressive symptoms compared to the healthy women, but the differences were not significant. In addition, high scores on paranoid ideation, somatization and obsessive compulsive symptoms were found in SS patients compared to the cancer and healthy controls. The results strongly suggest that psychiatric disorders are common in primary SS patients, who may need appropriate therapy.
最近有观点认为，原发性干燥综合征（SS）患者存在多种人格结构障碍和精神症状。为了进一步评估这一发现，我们对33例干燥综合征患者的敌意结构和精神症状进行了评估，并将结果与33名健康女性以及41名患有实体恶性肿瘤的女性进行了比较。所使用的心理测量工具为敌意与敌意方向问卷（HDHQ）和症状自评量表90修订版（SCL-90R）。与其他两组相比，SS患者报告的内向敌意水平较高。与健康女性相比，癌症患者和SS患者在焦虑和抑郁症状方面的得分更高，但差异不显著。此外，与癌症患者和健康对照组相比，SS患者在偏执观念、躯体化和强迫症状方面得分较高。结果强烈表明，精神障碍在原发性SS患者中很常见，这些患者可能需要适当的治疗。
