DeJesus Antonia, Turek Bradley J, Galban Evelyn, Suran Jantra Ngosuwan
BluePearl Veterinary Hospital, 410 W55th St, New York, NY, 10019.
Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey Street, Philadelphia, PA, 19104.
Vet Radiol Ultrasound. 2018 Mar;59(2):E17-E21. doi: 10.1111/vru.12456. Epub 2016 Nov 28.
A domestic shorthair kitten was presented for evaluation and further treatment of seizures. Magnetic resonance imaging of the brain revealed a large multilobulated mass in the third ventricle extending into the right lateral ventricle with secondary obstructive hydrocephalus. The mass was homogeneously isointense to gray matter on T2W, T2-FLAIR, T2 W, T1W, and ADC images, and hyperintense on DW-EPI. There was no appreciable contrast enhancement. Seizures were managed medically and with subsequent ventriculoperitoneal shunt placement. Clinical status later deteriorated and the cat was euthanized. Histopathology confirmed that the mass was the result of neuronal heterotopia. To the authors' knowledge this is the first report of neuronal heterotopia in a cat.
一只家养短毛小猫因癫痫发作前来评估并接受进一步治疗。脑部磁共振成像显示第三脑室内有一个大的多叶状肿块,延伸至右侧脑室,继发梗阻性脑积水。该肿块在T2加权、T2液体衰减反转恢复序列、质子密度加权、T1加权和表观扩散系数图像上与灰质呈均匀等信号,在扩散加权回波平面成像上呈高信号。没有明显的对比增强。癫痫发作通过药物治疗并随后进行了脑室腹腔分流术。猫的临床状况后来恶化,最终实施了安乐死。组织病理学证实该肿块是神经元异位的结果。据作者所知,这是猫身上神经元异位的首例报道。