DeJesus Antonia, Cohen Eli B, Galban Evelyn, Suran Jantra Ngosuwan
BluePearl Veterinary Partners, New York, NY, 10019.
The Department of Molecular Biomedical Sciences, NC State, College of Veterinary Medicine, Raleigh, NC, 27607.
Vet Radiol Ultrasound. 2017 May;58(3):326-333. doi: 10.1111/vru.12464. Epub 2016 Dec 20.
Intraventricular ependymoma is a rare type of feline intracranial neoplasia and published information on magnetic resonance imaging (MRI) characteristics is currently lacking. The purpose of this retrospective case series study was to describe the clinical and MRI characteristics of histopathologically confirmed intraventricular ependymomas in a group of cats. Five cats met inclusion criteria. In relation to normal gray matter, ependymomas appeared hyperintense on T2W, T2W-FLAIR, PD, and DW-EPI images; isointense on ADC images; and had subtle to strong contrast enhancement. Some variability was seen on T2*GRE and on T1W images with masses being isointense to hyperintense. Four ependymomas were small and homogeneous, and one was centrally cavitated. All cats had obstructive hydrocephalus, transtentorial herniation, and foramen magnum herniation. Perilesional edema was identified in most cats but was questionable in one. Intraventricular ependymoma should be considered as a differential diagnosis for cats with this combination of MRI signs.
脑室内室管膜瘤是一种罕见的猫颅内肿瘤,目前缺乏关于其磁共振成像(MRI)特征的公开信息。本回顾性病例系列研究的目的是描述一组经组织病理学证实的猫脑室内室管膜瘤的临床和MRI特征。五只猫符合纳入标准。与正常灰质相比,室管膜瘤在T2加权、T2加权液体衰减反转恢复(T2W-FLAIR)、质子密度(PD)和扩散加权回波平面成像(DW-EPI)图像上呈高信号;在表观扩散系数(ADC)图像上呈等信号;并具有轻微至明显的对比增强。在T2梯度回波(T2GRE)和T1加权图像上可见一些变化,肿块呈等信号至高信号。四个室管膜瘤较小且均匀,一个有中心空洞。所有猫均有梗阻性脑积水、小脑幕切迹疝和枕骨大孔疝。大多数猫可见病变周围水肿,但有一只猫的情况存疑。对于具有这种MRI表现组合的猫,应将脑室内室管膜瘤视为鉴别诊断之一。