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体育领域基因检测与研究的伦理:澳大利亚体育学院的立场声明

Ethics of genetic testing and research in sport: a position statement from the Australian Institute of Sport.

作者信息

Vlahovich Nicole, Fricker Peter A, Brown Matthew A, Hughes David

机构信息

Department of Sports Medicine, Australian Institute of Sport, Bruce, Australian Capital Territory, Australia.

CRN for Advancing Exercise and Sport Science, Bond University, University Drive, Robina, Queensland, Australia.

出版信息

Br J Sports Med. 2017 Jan;51(1):5-11. doi: 10.1136/bjsports-2016-096661. Epub 2016 Nov 29.

Abstract

As Australia's peak high-performance sport agency, the Australian Institute of Sport (AIS) has developed this position statement to address the implications of recent advances in the field of genetics and the ramifications for the health and well-being of athletes. Genetic testing has proven of value in the practice of clinical medicine. There are, however, currently no scientific grounds for the use of genetic testing for athletic performance improvement, sport selection or talent identification. Athletes and coaches should be discouraged from using direct-to-consumer genetic testing because of its lack of validation and replicability and the lack of involvement of a medical practitioner in the process. The transfer of genetic material or genetic modification of cells for performance enhancement is gene doping and should not be used on athletes. There are, however, valid roles for genetic research and the AIS supports genetic research which aims to enhance understanding of athlete susceptibility to injury or illness. Genetic research is only to be conducted after careful consideration of a range of ethical concerns which include the provision of adequate informed consent. The AIS is committed to providing leadership in delivering an ethical framework that protects the well-being of athletes and the integrity of sport, in the rapidly changing world of genomic science.

摘要

作为澳大利亚顶尖的高性能体育机构,澳大利亚体育学院(AIS)制定了本立场声明,以应对遗传学领域近期进展所带来的影响以及对运动员健康和福祉的后果。基因检测已在临床医学实践中证明具有价值。然而,目前尚无科学依据将基因检测用于提高运动成绩、体育选材或人才识别。由于缺乏验证性和可重复性,且在检测过程中没有医学从业者的参与,应劝阻运动员和教练使用直接面向消费者的基因检测。为提高成绩而转移遗传物质或对细胞进行基因改造属于基因兴奋剂,不应在运动员身上使用。然而,基因研究具有合理的作用,AIS支持旨在增进对运动员受伤或患病易感性理解的基因研究。基因研究只能在仔细考虑一系列伦理问题(包括提供充分的知情同意)之后进行。在基因组科学快速变化的世界中,AIS致力于在构建保护运动员福祉和体育诚信的伦理框架方面发挥引领作用。

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