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中国南通农村成年人代谢综合征及其危险因素的流行情况。

Prevalence of metabolic syndrome and its risk factors among rural adults in Nantong, China.

机构信息

Department of Epidemiology and Medical Statistics, School of Public Health, Nantong University, Nantong, Jiangsu, P.R. China.

Rugao Center for Diseases Prevention and Control, Nantong, Jiangsu, P.R. China.

出版信息

Sci Rep. 2016 Nov 30;6:38089. doi: 10.1038/srep38089.

Abstract

The prevalence of metabolic syndrome (MS) varies worldwide due to genetic and environmental factors. A population-based cross-sectional study, with 37,582 participants recruited in Nantong, China in 2007-2008 (stage I) and 2013 (stage II). Socio-demographic, lifestyle factors, disease history and fasting blood sample were collected. The prevalence of MS was much higher in 2013 (42.6%) than that in 2007-2008 (21.6%), which was significantly higher in older people in both stages. Participants with two or more familial history of diseases were associated with a higher MS prevalence compared to those who didn't have familial history of diseases. Total physical activity (PA) was associated with 24 and 19% decreased risk of MS in men and women. Occupational PA in moderate and vigorous intensity was associated with a 25%-45% decreased risk of MS. Female smokers who smoked more than 10 cigarettes per day or over 25 years were associated with 96 and 74% increased MS risk, respectively. The highest quartile of rice wine consumption was associated with a lower risk of MS with OR of 0.63 in women, compared with female non-drinkers. These findings indicated that PA and rice wine are two protective factors in MS prevention in rural areas of East China.

摘要

代谢综合征(MS)的患病率因遗传和环境因素在全球范围内有所不同。一项基于人群的横断面研究,于 2007-2008 年(阶段 I)和 2013 年(阶段 II)在中国南通招募了 37582 名参与者。收集了社会人口统计学、生活方式因素、疾病史和空腹血样。2013 年(42.6%)的 MS 患病率明显高于 2007-2008 年(21.6%),两个阶段的老年人患病率均较高。与没有家族病史的人相比,有两种或两种以上家族病史的人患 MS 的几率更高。与不进行任何体力活动相比,男性和女性的总体力活动(PA)分别降低 24%和 19%患 MS 的风险。中等和剧烈强度的职业性体力活动与 MS 风险降低 25%-45%相关。每天吸烟超过 10 支或吸烟超过 25 年的女性吸烟者患 MS 的风险分别增加 96%和 74%。与不饮酒的女性相比,饮用米酒最高四分位数的女性患 MS 的风险较低,比值比为 0.63。这些发现表明,PA 和米酒是华东农村地区预防 MS 的两个保护因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51ce/5128865/2a43b9f44525/srep38089-f1.jpg

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