斯里兰卡贾夫纳地区18岁以上泰米尔人的代谢综合征患病率及相关因素

Prevalence and factors associated with metabolic syndrome among Tamils aged over 18 years in Jaffna district, Sri Lanka.

作者信息

Amarasinghe Sivarathy, Balakumar Sandrasegarampillai, Arasaratnam Vasanthy

机构信息

Department of Biochemistry, Faculty of Medicine, University of Jaffna, Jaffna, Sri Lanka.

出版信息

J Diabetes Metab Disord. 2015 Jul 22;14:61. doi: 10.1186/s40200-015-0190-x. eCollection 2015.

DOI:10.1186/s40200-015-0190-x

PMID:26203430

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4511035/

Abstract

BACKGROUND

The aim was to determine the prevalence and factors associated with Metabolic Syndrome (MS) among adults aged over 18 years in Jaffna district, Sri Lanka.

METHODS

This study was carried out as a community based cross sectional descriptive study in Jaffna district, Sri Lanka. Multistage stratified cluster sampling technique was employed. Total sample size was 544. An interviewer administrated questionnaire was used to gather data. Waist circumference (WC) and blood pressure (BP) measurements were recorded in standard method. Overnight fasting blood samples were obtained from all subjects. Fasting plasma glucose (FPG), high density lipoprotein (HDL), and triacylglycerols were analyzed by the enzymatic colorimetric assay (Semi Automated analyser Teco Diagnostics TC 3300). Modified National Cholesterol Education Program's Adult Treatment Panel III (NCEP ATP III) criterion was used to define the MS.

RESULTS

Sample response rate was 95.3 %. Of them, 43.8 % (n = 224) was male. Prevalence of central obesity (WC for male ≥102 cm, female ≥88 cm) was 16.2 %. Prevalence of raised FPG (≥100 mg/dL), hypertriacylglycerolaemia (≥150 mg/dl), low level of HDL cholesterol (<40 mg/dL in males, <50 mg/dL in females) and raised BP (systolic BP ≥130 or diastolic BP ≥85 mmHg) were 23.9, 25, 79.3 and 36.6 % respectively. Prevalence of MS was 24.1 % (n = 123, 95 % CI: 20.4-28) and it was 26.8 and 21.9 % among males and females respectively. Participants living in urban area had higher prevalence of MS when compared with participants living in rural area (P = 0.015). Older age (P < 0.001) and smoking (P = 0.005) were risk factor for development of MS. Prevalence of MS among the participants with sedentary and active lifestyle was 29.9 and 23.7 % respectively.

CONCLUSION

One out of four had MS. Old age, urban living and smoking carried higher risk for developing MS in Jaffna community.

摘要

背景

目的是确定斯里兰卡贾夫纳地区18岁以上成年人中代谢综合征（MS）的患病率及其相关因素。

方法

本研究在斯里兰卡贾夫纳地区开展，是一项基于社区的横断面描述性研究。采用多阶段分层整群抽样技术。总样本量为544。通过访谈员管理的问卷收集数据。采用标准方法记录腰围（WC）和血压（BP）。采集所有受试者的过夜空腹血样。采用酶比色法（半自动分析仪Teco Diagnostics TC 3300）分析空腹血糖（FPG）、高密度脂蛋白（HDL）和甘油三酯。采用改良的美国国家胆固醇教育计划成人治疗组第三次报告（NCEP ATP III）标准定义代谢综合征。

结果

样本应答率为95.3%。其中，43.8%（n = 224）为男性。中心性肥胖（男性WC≥102 cm，女性WC≥88 cm）的患病率为16.2%。空腹血糖升高（≥100 mg/dL）、高甘油三酯血症（≥150 mg/dl）、HDL胆固醇水平低（男性<40 mg/dL，女性<50 mg/dL）和血压升高（收缩压≥130或舒张压≥85 mmHg）的患病率分别为23.9%、25%、79.3%和36.6%。代谢综合征的患病率为24.1%（n = 123，95%CI：20.4 - 28），男性和女性分别为26.8%和21.9%。与居住在农村地区的参与者相比，居住在城市地区的参与者代谢综合征患病率更高（P = 0.015）。年龄较大（P < 0.001）和吸烟（P = 0.005）是代谢综合征发生的危险因素。久坐和活跃生活方式的参与者中代谢综合征的患病率分别为29.9%和23.7%。