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马来西亚某公立大学员工中代谢综合征及其相关危险因素的流行情况。

Prevalence of metabolic syndrome and its associated risk factors among staffs in a Malaysian public university.

机构信息

Department of Community Health, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.

Department of Family Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.

出版信息

Sci Rep. 2021 Apr 14;11(1):8132. doi: 10.1038/s41598-021-87248-1.

Abstract

Public health systems are concerned with the commensurate rise of metabolic syndrome (MetS) incidence across populations worldwide, due to its tendency to amplify greater risk of diabetes and cardiovascular diseases within communities. This study aimed to determine the prevalence of MetS and its associated risk factors among staffs in a Malaysian public university. A cross-sectional study was conducted among 538 staffs from the Universiti Kebangsaan Malaysia (UKM) between April and June 2019. MetS was defined according to JIS "Harmonized" criteria. A questionnaire that consisted of items on socio-demographics, lifestyle risk behaviors and personal medical history information was administered to participants. Subsequently, a series of physical examination and biochemical assessment was conducted at the hall or foyer of selected faculties in the university. Descriptive and inferential statistics were conducted using SPSS version 22.0. Multivariate models were yielded to determine the risk factors associated with MetS. Statistical significance was set at P < 0.05. The overall prevalence of MetS was 20.6%, with men having greater prevalence than women (24.9% vs. 18.3%). Prevalence of MetS increased with age. Factors contributed to MetS in the overall sample were BMI, hypertension, diabetes and physical activity of moderate intensity. Diabetes and hypertension were significantly associated with MetS in men, whereas BMI, diabetes and hyperlipidemia were significantly associated with MetS in women. Lifestyle behaviors and cardio-metabolic risk factors were associated with MetS for the overall sample, and across genders.

摘要

公共卫生系统关注的是代谢综合征(MetS)在全球范围内的发病率相应上升,因为它有加剧社区内糖尿病和心血管疾病风险的倾向。本研究旨在确定马来西亚一所公立大学员工中 MetS 的患病率及其相关危险因素。2019 年 4 月至 6 月期间,在马来西亚国民大学(UKM)的 538 名员工中进行了横断面研究。MetS 根据 JIS“协调”标准定义。向参与者发放了一份包括社会人口统计学、生活方式风险行为和个人病史信息的问卷。随后,在大学的选定学院的大厅或门厅进行了一系列体格检查和生化评估。使用 SPSS 版本 22.0 进行描述性和推断性统计。多变量模型用于确定与 MetS 相关的危险因素。统计显著性设置为 P < 0.05。MetS 的总体患病率为 20.6%,男性患病率高于女性(24.9%比 18.3%)。MetS 的患病率随年龄增长而增加。总体样本中导致 MetS 的因素是 BMI、高血压、糖尿病和中等强度的身体活动。糖尿病和高血压与男性的 MetS 显著相关,而 BMI、糖尿病和血脂异常与女性的 MetS 显著相关。生活方式行为和心血管代谢危险因素与总体样本以及各性别中的 MetS 相关。

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